Proteasome 20S C2 Products

Antibodies
Proteasome 20S C2 Antibody
Proteasome 20S C2 Antibody
NB600-1016
Species: Hu, Mu, Rt, Rb, Ye
Applications: WB, IHC, IP
Host: Rabbit Polyclonal
Proteasome 20S C2 Antibody
Proteasome 20S C2 Antibody
NBP1-81768
Species: Hu, Mu, Rt, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P, IF
Host: Rabbit Polyclonal
Proteasome 20S C2 Antibody (1 ...
Proteasome 20S C2 Antibody (1D9-1C7)
H00005682-M01
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
Kits
Proteasome 20S C2 Assay Kit
Proteasome 20S C2 Assay Kit
KA1431
Species: Ma
Applications: Func
Proteasome 20S C2 Assay Kit
Proteasome 20S C2 Assay Kit
KA1352
Applications: Func
Lysates
Proteasome 20S C2 Overexpress ...
Proteasome 20S C2 Overexpression L...
NBL1-14871
Applications: WB
Proteins
Proteasome 20S C2 Recombinant ...
Proteasome 20S C2 Recombinant Prot...
NBP2-37908PEP
Species: Hu
Applications: AC
Proteasome 20S C2 Recombinant ...
Proteasome 20S C2 Recombinant Prot...
NBP1-81768PEP
Species: Hu
Applications: AC
Proteasome 20S C2 Recombinant ...
Proteasome 20S C2 Recombinant Protein
NBP1-72482
Species: Hu
Applications: PAGE
RNAi
Proteasome 20S C2 RNAi
Proteasome 20S C2 RNAi
H00005682-R01V
Species: Hu
Applications: WB, RNAi SP
Proteasome 20S C2 RNAi
Proteasome 20S C2 RNAi
H00005682-R02
Species: Hu
Proteasome 20S C2 RNAi
Proteasome 20S C2 RNAi
H00005682-R01
Species: Hu

Description

The proteasome is widely recognised as the central enzyme of non-lysosomal protein degradation. It is responsible for intracellular protein turnover and it is also critically involved in many regulatory processes and, in higher eukaryotes, in antigen processing. The 26S proteasome is the key enzyme of the ubiquitin/ATP-dependent pathway of protein degradation. The catalytic core of this unusually large (2000kDa, 450A in length) complex is formed by the 20S proteasome, a barrel shaped structure shown by electron microscopy to comprise of four rings each containing seven subunits. Based on sequence similarity, all fourteen 20S proteasomal subunit sequences may be classified into two groups, alpha and beta, each group having distinct structural and functional roles. The alpha-subunits comprise the outer rings and the beta-subunits the inner rings of the 20S proteasome. Observations of the eukaryotic proteasome and analysis of subunit sequences indicate that each ring contains seven different subunits (alpha 7 beta 7 beta 7 alpha 7) with a member of each sub-family represented in each particle. Each subunit is located in a unique position within the alpha- or beta-rings (ref 1). 20S Proteasomes degrade only unfolded proteins in an energy-independent manner, whereas 26S proteasomes degrade native and ubiquitinylated proteins in an ATP-dependent manner. The native protein substrates are recognised by subunits, some with ATP binding sites, of the outer 19S caps of the 26S proteasome (ref 2).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 5682
Alternate Names
  • PSC2
  • Macropain subunit C2
  • protein P30-33K
  • MGC23915
  • proteasome subunit, alpha-type, 1
  • MGC22853
  • proteasome subunit nu
  • MGC21459
  • proteasome subunit alpha type-1
  • MGC1667
  • macropain subunit nu
  • MGC14751
  • EC 3.4.25.1
  • MGC14575
  • PROS-30
  • MGC14542
  • NU30 kDa prosomal protein
  • HC2Proteasome nu chain
  • PROS30Proteasome component C2
  • Multicatalytic endopeptidase complex subunit C2
  • proteasome (prosome, macropain) subunit, alpha type, 1

Research Areas for Proteasome 20S C2

Find related products by research area and learn more about each of the different research areas below.

Neuroscience
Ubiquitin Proteasome Pathway

PTMs for Proteasome 20S C2

Learn more about PTMs related to Proteasome 20S C2.

Phosphorylation
Deacetylation
Acetylation

Bioinformatics Tool for Proteasome 20S C2

Discover related pathways, diseases and genes to Proteasome 20S C2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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