Prion protein Products

Antibodies
Prion protein Antibody
Prion protein Antibody
NB100-56605
Species: Av, Bv, Sh
Applications: WB
Host: Rabbit Polyclonal
Prion protein Antibody (C16-S ...
Prion protein Antibody (C16-S)
NBP1-71679
Species: Hu, Mu, Bv, Sh
Applications: WB, ELISA, IHC, IHC-Fr, IHC-P, IP
Host: Rabbit Monoclonal
Prion protein Antibody
Prion protein Antibody
NB100-56604
Species: Bv, Sh
Applications: WB
Host: Rabbit Polyclonal
Lysates
Prion protein Overexpression ...
Prion protein Overexpression Lysat...
NBL1-14799
Applications: WB
Proteins
Prion protein Recombinant Pro ...
Prion protein Recombinant Protein ...
NBP1-92285PEP
Species: Hu
Applications: AC
Prion protein Recombinant Pro ...
Prion protein Recombinant Protein ...
NBP2-38508PEP
Species: Hu
Applications: AC
Prion protein Recombinant Pro ...
Prion protein Recombinant Protein
NBP2-23360
Species: Hu
Applications: PAGE

Description

Prion diseases are transmissible neurodegenerative disorders which affect a range of mammalian species. In humans they can be inherited and sporadic as well as acquired by exposure to human prions. Prions appear to be composed principally of a conformational isomer of host-encoded prion protein and propagate by recruitment of cellular prion protein (1). The function of the cellular prion protein (PrP) is still poorly understood. It has been proposed that one unprecedented role for PrP is against Bax-mediated neuronal apoptosis. It has been shown that PrP potently inhibits Bax-induced cell death in human primary neurons (2). An impaired synaptic inhibition may be involved in the epileptiform activity seen in Creutzfeldt-Jakob and other neurodegenerative diseases and it is believed that loss of function of PrP may contribute to the early synaptic loss and neuronal degeneration seen in these diseases (3).

Bioinformatics

Entrez Human
Mouse
Rat
Sheep
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 5621
Alternate Names
  • prion-related protein
  • CJD
  • prion protein PrP
  • prion protein (p27-30)
  • fatal familial insomnia)
  • CD230
  • PRIPMGC26679
  • GSS
  • prion protein

Research Areas for Prion protein

Find related products by research area and learn more about each of the different research areas below.

Neuroscience
Stem Cell Markers

Bioinformatics Tool for Prion protein

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