PRG2 Products

Antibodies
PRG2 Antibody
PRG2 Antibody
NBP2-19928
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
PRG2 Antibody
PRG2 Antibody
H00005553-B01P
Species: Hu
Applications: WB
Host: Mouse Polyclonal
PRG2 Antibody
PRG2 Antibody
NBP1-88573
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
PRG2 Overexpression Lysate (D ...
PRG2 Overexpression Lysate (Denatu...
H00005553-T01
Species: Hu
Applications: WB
PRG2 Overexpression Lysate (N ...
PRG2 Overexpression Lysate (Native)
NBL1-14752
Applications: WB
Proteins
Recombinant Human PRG2 Protei ...
Recombinant Human PRG2 Protein
H00005553-Q01
Species: Hu
Applications: WB, ELISA, PA
PRG2 Recombinant Protein Anti ...
PRG2 Recombinant Protein Antigen
NBP1-88573PEP
Species: Hu
Applications: AC
RNAi
PRG2 RNAi
PRG2 RNAi
H00005553-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

PRG2, also known as Bone marrow proteoglycan, is a 222 amino acid protein that is 25 kDa, found in high levels of the proform in placenta and pregnancy serum, may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions; is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases; and the proform acts as a proteinase inhibitor, reducing the activity of PAPPA. Disease research is currently being studied in relation to PRG2 and malignant peripheral nerve sheath tumor, epithelioid malignant peripheral nerve sheath tumor, ocular cicatricial pemphigoid, cicatricial pemphigoid, giant papillary conjunctivitis, vernal keratoconjunctivitis, corneal ulcer, allergic rhinitis, eosinophilic gastroenteritis, papillary conjunctivitis, hypereosinophilic syndrome, eosinophilia, pulmonary eosinophilia,connective tissue disease, kimura disease, rhinitis, retinal detachment, keratoconjunctivitis, eosinophilic esophagitis, and familial eosinophilia. The protein has been shown to interact with CHD3, PAPPA, PRKCZ, AGT, CSF2, and other proteins in MAPK Signaling, Molecular Mechanisms of Cancer, PTEN Pathway, Transendothelial Migration of Leukocytes, UPA-UPAR Pathway, Selected targets of C/EBPbeta and Asthma pathways.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 5553
Alternate Names
  • Proteoglycan 2
  • bone marrow proteoglycan
  • proteoglycan 2 preproprotein
  • MGC14537
  • natural killer cell activator
  • MBP1
  • BMPGeosinophil major basic protein
  • MBPeosinophil granule major basic protein
  • bone-marrow proteoglycan
  • proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granulemajor basic protein)

Research Areas for PRG2

Find related products by research area and learn more about each of the different research areas below.

Asthma
Immunology

PTMs for PRG2

Learn more about PTMs related to PRG2.

Demethylation
Cleavage
Methylation

Bioinformatics Tool for PRG2

Discover related pathways, diseases and genes to PRG2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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