PHAPIII Products

Antibodies
PHAPIII Antibody
PHAPIII Antibody
NB100-94274
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
Proteins
PHAPIII Peptide
PHAPIII Peptide
NBP1-77227PEP
Species: Hu
Applications: AC

Description

Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis (1). PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.

Bioinformatics

Product By Gene ID 8125
Alternate Names
  • C15orf1
  • I1PP2A
  • PHAPI
  • PHAP1
  • HPPCn
  • PP32
  • MAPM
  • LANP
  • acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
  • ANP32A

PTMs for PHAPIII

Learn more about PTMs related to PHAPIII.

Phosphorylation
Acetylation
Dephosphorylation
Cleavage
Biotinylation
Oxidation

Bioinformatics Tool for PHAPIII

Discover related pathways, diseases and genes to PHAPIII. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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