PEDF R/PNPLA2/ATGL Products

Antibodies
PEDF R/PNPLA2/ATGL Antibody [ ...
PEDF R/PNPLA2/ATGL Antibody [Uncon...
AF5365
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC
Host: Sheep Polyclonal
Lysates
PEDF R/PNPLA2/ATGL Overexpres ...
PEDF R/PNPLA2/ATGL Overexpression ...
H00057104-T01
Species: Hu
Applications: WB
PEDF R/PNPLA2/ATGL Overexpres ...
PEDF R/PNPLA2/ATGL Overexpression ...
NBL1-14554
Applications: WB
Proteins
PEDF R/PNPLA2/ATGL Blocking P ...
PEDF R/PNPLA2/ATGL Blocking Peptide
NB110-41536PEP
Species: Hu
PEDF R/PNPLA2/ATGL Recombinan ...
PEDF R/PNPLA2/ATGL Recombinant Pro...
NBP2-58046PEP
Species: Hu
Applications: B/N, Ctrl
PEDF R/PNPLA2/ATGL Recombinan ...
PEDF R/PNPLA2/ATGL Recombinant Pro...
NBP2-57480PEP
Species: Hu
Applications: B/N, Ctrl
RNAi
PEDF R/PNPLA2/ATGL RNAi
PEDF R/PNPLA2/ATGL RNAi
H00057104-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Patatin-like phospholipase domain-containing protein 2 (PNPLA2), also known as adipose triglyceride lipase (ATGL), is a lipolytic enzyme required for mobilization of fatty acids from triglyceride stores in adipose tissue. Until recently, hormone-sensitive lipase (HSL) was the only enzyme known to hydrolyze triglycerides in mammalian adipose tissue. However, ATGL has now been shown to catalyze the initial step of triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Thus, ATGL and HSL coordinate to catabolize stored triglycerides in adipose tissue of mammals.

Defects in PNPLA2 can lead to neutral lipid storage disease with myopathy (NLSDM), a neutral lipid storage disorder with myopathy but without ichthyosis.

ATGL antibodies can serve as useful tools for adipocyte studies and research on triglyceride processing and fat storage.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 57104
Alternate Names
  • EC 3.1.1.3
  • Transport-secretion protein 2
  • TTS2.2
  • Desnutrin
  • IPLA2-zeta
  • triglyceride hydrolase
  • Pigment epithelium-derived factor
  • transport-secretion protein 2.2
  • Calcium-independent phospholipase A2
  • patatin-like phospholipase domain-containing protein 2-like
  • Adipose triglyceride lipase
  • patatin-like phospholipase domain-containing protein 2
  • desnutrin
  • PEDF-R
  • TTS-2.2
  • TTS2DKFZp667M109
  • ATGL1110001C14Rik
  • FP17548
  • patatin-like phospholipase domain containing 2

Research Areas for PEDF R/PNPLA2/ATGL

Find related products by research area and learn more about each of the different research areas below.

Autophagy
Cancer
Diabetes Research
Lipid and Metabolism
Lipid Droplets
Signal Transduction

PTMs for PEDF R/PNPLA2/ATGL

Learn more about PTMs related to PEDF R/PNPLA2/ATGL.

Phosphorylation
Oxidation
Acylation

Bioinformatics Tool for PEDF R/PNPLA2/ATGL

Discover related pathways, diseases and genes to PEDF R/PNPLA2/ATGL. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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