PDGF R alpha Products

Antibodies
PDGF R alpha Antibody
PDGF R alpha Antibody
AF1062
Species: Mu
Applications: WB, IHC, Neut
Host: Goat Polyclonal
PDGF R alpha Antibody
PDGF R alpha Antibody
AF-307-NA
Species: Hu
Applications: WB, IHC, Neut
Host: Goat Polyclonal
PDGF R alpha Antibody (35248) ...
PDGF R alpha Antibody (35248) [Unc...
MAB322
Species: Hu
Applications: WB, IHC, Neut
Host: Mouse Monoclonal
Conjugate Catalog # Availability Size Price
Antibody Pairs
PDGF R alpha Antibody Pair
PDGF R alpha Antibody Pair
H00005156-PW1
Species: Hu
Applications: WB, IP
Lysates
PDGF R alpha Overexpression L ...
PDGF R alpha Overexpression Lysate...
H00005156-T01
Species: Hu
Applications: WB
Proteins
PDGF R alpha Recombinant Prot ...
PDGF R alpha Recombinant Protein
NBP1-72398
Species: Hu
Applications: PAGE
RNAi
PDGF R alpha RNAi
PDGF R alpha RNAi
H00005156-R04
Species: Hu

Description

Platelet-derived growth factor receptors exhibit tyrosine-protein kinase activity and have been implicated in the control of cell proliferation, survival and migration. PDGF receptors, PDGFR-alpha and PDGFR-beta, have 5 extracellular immunoglobulin-like domains and an intracellular tyrosine kinase domain. Upon binding a PDGF, the receptors form homo-and heterodimers. Dimerization of the receptors results in phosphorylation in the complex. More than 10 different SH2-domain-containing molecules have been shown to bind to different autophosphorylation sites in the PDGF-alpha and beta receptors. PDGF alpha receptors are expressed in oligodendrocyte progenitor cells and PDGF beta receptors are expressed on neurons.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Mouse
Product By Gene ID 5156
Alternate Names
  • CD140A
  • EC 2.7.10
  • CD140a
  • rearranged-in-hypereosinophilia-platelet derived growth factor receptor alphafusion protein
  • EC 2.7.10.1
  • PDGFRA/BCR fusion
  • CD140a antigen
  • alpha-type platelet-derived growth factor receptor
  • CD140 antigen-like family member A
  • RHEPDGFRA
  • PDGF-R-alpha
  • PDGFR2
  • MGC74795
  • platelet-derived growth factor receptor, alpha polypeptide

Research Areas for PDGF R alpha

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Protein Kinase

Bioinformatics Tool for PDGF R alpha

Discover related pathways, diseases and genes to PDGF R alpha. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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