p97/VCP Products

Antibodies
p97/VCP Antibody
p97/VCP Antibody
NB100-1558
Species: Hu, Mu, Rt, Ze, Po, Bv
Applications: WB, ICC/IF, IHC, IP
Host: Rabbit Polyclonal
p97/VCP Antibody
p97/VCP Antibody
NB100-1557
Species: Hu, Mu, Rt, Po, Bv, Ze
Applications: WB, IHC, IP
Host: Rabbit Polyclonal
p97/VCP Antibody (4A8)
p97/VCP Antibody (4A8)
H00007415-M03
Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC
Host: Mouse Monoclonal
Lysates
p97/VCP Overexpression Lysate ...
p97/VCP Overexpression Lysate
NBL1-17707
Species: Hu
Applications: WB
Proteins
Recombinant Human p97/VCP GST ...
Recombinant Human p97/VCP GST (N-T...
H00007415-P02
Species: Hu
Applications: WB, ELISA, ICC/IF, MA, AP
Recombinant Human p97/VCP GST ...
Recombinant Human p97/VCP GST (N-T...
H00007415-Q01
Species: Hu
Applications: WB, ELISA, MA, AP
Recombinant Human p97/VCP GST ...
Recombinant Human p97/VCP GST (N-T...
H00007415-Q02
Species: Hu
Applications: WB, ELISA, MA, AP

Description

Valosin-containing protein (VCP or p97) belongs to the AAA (ATPase associated activities) family and acts as a molecular chaperone to a wide variety of cellular activities. Some of these activities include the alteration of both nuclear and mitotic golgi membranes, ubiquitin-proteasome dependent protein degradation, regulation of the NF-kappa b pathway, and extraction of membrane proteins. VCP has been shown to contain a substrate binding domain (N) and two conserved ATPase domains (D1 and D2). The three dimensional structure of VCP resembles that of a cylinder with the D1 and D2 stacked upon one another in a homo-hexameric ring formation. VCP is involved in the formation of neuronal inclusion bodies in neurodegenerative disease such as Parkinson's Disease.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Human
Alternate Names
  • 15S Mg(2+)-ATPase p97 subunit
  • IBMPFDMGC8560
  • MGC131997
  • p97
  • TER ATPase
  • TERA
  • transitional endoplasmic reticulum ATPase
  • valosin containing protein
  • Valosin-containing proteinMGC148092
  • yeast Cdc48p homolog

Research Areas for p97/VCP

Find related products by research area and learn more about each of the different research areas below.

Cellular Markers
DNA Repair
Membrane Trafficking and Chaperones
Signal Transduction