p19ARF Products

p19ARF Peptide
p19ARF Peptide
Species: Hu


p19ARF (mouse) and p14ARF (human) has become an important player in cell cycle regulation. In mice, tumor suppressor effects appear to be mediated by interactions between p19ARF and the p53 tumor suppressor protein. p19ARF counters uncontrolled proliferation and oncogenic signals in p53 dependent pathways. Proteins encoded by the INK4a/ARF locus also play a role in Abelson virus transformation. Both p16INK4a and p19ARF are expressed in many cells as they emerge from the apoptotic crisis that characterizes the transformation process. p19ARF is an important part in cellular defense against transforming signals from the Abl oncoprotein, providing direct evidence that the p19ARF-p53 regulatory loop plays an important role in lymphoma induction.


Uniprot Mouse
Product By Gene ID 12578
Alternate Names
  • p19Arf
  • p19ARF
  • p19
  • p16INK4A
  • p16INK4a
  • p16-INK4a
  • p16
  • p16-INK4
  • p14
  • p14ARF
  • INK4a
  • cyclin-dependent kinase inhibitor 2A
  • P16
  • cell cycle negative regulator beta
  • MTS-1
  • CDK4 inhibitor p16-INK4
  • CDKN2
  • TP16
  • Multiple tumor suppressor 1
  • P19ARF
  • Cyclin-dependent kinase 4 inhibitor A
  • P19
  • INK4
  • P16INK4A
  • ARF
  • MLMP16INK4
  • CMM2P16-INK4A
  • MTS1P14
  • INK4A
  • cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)

Research Areas for p19ARF

Find related products by research area and learn more about each of the different research areas below.

ABC Transporters
Cell Biology
Cell Cycle and Replication
Chromatin Research
DNA Repair
MAP Kinase Signaling
p53 Pathway
Transcription Factors and Regulators
Tumor Suppressors

Bioinformatics Tool for p19ARF

Discover related pathways, diseases and genes to p19ARF. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Vizit™, under license from BioVista Inc.

Related p19ARF Blog Posts

Check out the latest blog posts on p19ARF.
You can't be without me - SNF5
The protein encoded by SNF5 is a component of the chromatin-remodeling protein complex responsible for relieving repressive chromatin structures by allowing the transcriptional machinery to access targets more effectively. SNF5 has been found to be a...    Read more.
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