The GRIN3A (NMDAR3A) gene encodes a 1,115 amino acid long, 126 kDA glutamate receptor iontrophic, NMDA 3A that is a glycine controlled receptor that functions in glutamate-gated ion channels with reduced single-channel conductance, calcium, and voltage-sensitivity to magnesium. Additionally, it works in the creation of dendritic spines. GRIN3B functions in glutamic acid signaling, the pathogenesis of ALS, the neuroactive ligand-receptor interaction, and the dopamine DARPP32 feedback onto cAMP pathway. The GRIN3A gene interacts with DGL4, GRIN1, GRIN2A, GRIN2B, and DYNLL1. This gene has been linked to HIV type 1, neuroblastoma, pain syndrome, bipolar disorder, nicotine dependence, prostate cancer, schizophrenia, immunodeficiency, and Alzheimer's disease.
|Product By Gene ID
- N-methyl-D-aspartate receptor subtype 3A
- glutamate NMDA receptor subunit 3A
- glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
Bioinformatics Tool for NMDAR3A
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