Methylated Lysine Products

Methylated Lysine Antibody
Methylated Lysine Antibody
Species: All-NA
Applications: WB, ELISA, ICC/IF, IP
Host: Rabbit Polyclonal
Methylated Lysine Antibody
Methylated Lysine Antibody
Species: Av, Ma
Applications: WB, ELISA, IP
Host: Rabbit Polyclonal


Post-translational modifications of proteins play critical roles in the regulation and function of many known biological processes. Proteins can be post-translationally modified in many different ways, and a common posttranscriptional modification of Lysine involves methylation (1). Lysine can be methylated once, twice or three times by lysine methyltransferases. The transfer of methyl groups from S-adenosyl methionine to histones is catalyzed by enzymes known as histone methyltransferases. Histones which are methylated on certain residues can act epigenetically to repress or activate gene expression (1, 2). The transcriptional repressor SUV39H1 can encode novel enzymes which selectively methylate histone H3 at lysine 9. SUV39H1 places a methyl marker on histone H3, which is then recognized by HP1 through its chromo domain. This model may also explain the stable inheritance of the heterochromatic state (3). Some studies have also speculated a stimulatory role for transcription by methylated histone lyside 4 due to its presence at active transcription sites (4-6).


Alternate Names
  • Dimethylysine
  • Methyl lysine
  • N epsilon dimethyl lysine
  • N epsilon mono methyllysine
  • N epsilon trimethyl lysine
  • N(epsilon) trimethyl lysine
  • Trimethyl lysine

Research Areas for Methylated Lysine

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