metabotropic Glutamate Receptor 1a Products

Antibodies
metabotropic Glutamate Recept ...
metabotropic Glutamate Receptor 1a...
NB110-39033
Species: Hu, Mu, Rt, Ch
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P
Host: Rabbit Polyclonal
metabotropic Glutamate Recept ...
metabotropic Glutamate Receptor 1a...
NB100-93555
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-Fr
Host: Rabbit Polyclonal
metabotropic Glutamate Recept ...
metabotropic Glutamate Receptor 1a...
NB300-123
Species: Rt
Applications: WB, IHC, IHC-Fr
Host: Rabbit Polyclonal

Description

The Metabotropic Glutamate Receptor mGluR1 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. mGluR1 and mGluR5 are group I receptors that have been shown to activate phospholipase C. Alternative splice variants of the mGluR1 gene have been described, but their full-length nature has not been determined. Inflammation results in the activation of mGluR1 and mGluR5 in dorsal horn neurons of the spinal cord, leading to extracellular signal-regulated kinase (ERK) activation, which is required for nociceptive plasticity and enhanced pain. mGluR1 has been reported in various regions of the brain and spinal cord. ESTs have been isolated from brain and eye libraries. Caution: GLUR1 refers to Ionotropic Glutamate Receptor 1, not to Metabotropic Glutamate Receptor 1 (mGLUR1).

Bioinformatics

Entrez Human
Mouse
Mouse
Rat
Rat
Uniprot Human
Rat
Product By Gene ID 2911
Alternate Names
  • mGluR1
  • MGLUR1A
  • metabotropic glutamate receptor 1
  • GRM1A
  • MGLUR1GPRC1AmGlu1
  • glutamate receptor, metabotropic 1

Research Areas for metabotropic Glutamate Receptor 1a

Find related products by research area and learn more about each of the different research areas below.

GPCR
Metabotropic Glutamate Receptors
Neuronal Cell Markers
Neuroscience
Neurotransmission
Vision

PTMs for metabotropic Glutamate Receptor 1a

Learn more about PTMs related to metabotropic Glutamate Receptor 1a.

Cleavage
Phosphorylation
Methylation
Demethylation
Glycosylation
Acetylation

Bioinformatics Tool for metabotropic Glutamate Receptor 1a

Discover related pathways, diseases and genes to metabotropic Glutamate Receptor 1a. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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