LRDD Products

Antibodies
LRDD Antibody (Anto-1)
LRDD Antibody (Anto-1)
NBP1-97595
Species: Hu
Applications: WB, IHC, IHC-P
Host: Mouse Monoclonal
LRDD Antibody
LRDD Antibody
NBP1-57991
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
LRDD Antibody
LRDD Antibody
NBP1-57990
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Lysates
LRDD Overexpression Lysate (N ...
LRDD Overexpression Lysate (Native)
NBL1-12662
Applications: WB

Description

The protein encoded by the LRDD gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. (provided by RefSeq)

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 55367
Alternate Names
  • leucine-rich repeat and death domain-containing protein
  • p53-induced protein with a death domain
  • MGC16925
  • PIDDDKFZp434D229
  • leucine-rich repeats and death domain containing

PTMs for LRDD

Learn more about PTMs related to LRDD.

Cleavage
Phosphorylation
Sumoylation
Ubiquitination
Glycosylation
Acetylation

Bioinformatics Tool for LRDD

Discover related pathways, diseases and genes to LRDD. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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