Low Density LRP Products

Antibodies
Low Density LRP Antibody
Low Density LRP Antibody
H00004035-B01P
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Polyclonal
Low Density LRP Antibody (8B8 ...
Low Density LRP Antibody (8B8)
NB200-522
Species: Rb
Applications: WB, Flow, IHC, IHC-Fr, IHC-P
Host: Mouse Monoclonal
Low Density LRP Antibody (Alp ...
Low Density LRP Antibody (Alpha 2M...
NBP1-40121
Species: Hu
Applications: WB, ELISA, Flow, IHC-Fr, IHC-P, IP
Host: Mouse Monoclonal
Lysates
Low Density LRP Overexpressio ...
Low Density LRP Overexpression Lys...
H00004035-T01
Species: Hu
Applications: WB
Low Density LRP Overexpressio ...
Low Density LRP Overexpression Lys...
NBL1-12668
Applications: WB
Proteins
Low Density LRP Recombinant P ...
Low Density LRP Recombinant Protein
H00004035-P01
Species: Hu
Applications: WB, ELISA, PA
Low Density LRP Recombinant P ...
Low Density LRP Recombinant Protein
H00004035-G01
Species: Hu
Low Density LRP Recombinant P ...
Low Density LRP Recombinant Protei...
NBP2-48497PEP
Species: Hu
Applications: AC
RNAi
Low Density LRP RNAi
Low Density LRP RNAi
H00004035-R01
Species: Hu

Description

Low density lipoprotein receptor-related protein (also known as low density LRP, LRP1, alpha-2-macroglobulin receptor or Apolipoprotein E receptor) is an endocytotic receptor that is involved both in endocytosis and in phagocytosis of apoptotic cells. It is required for early embryonic development, is involved in cellular lipid homeostasis, and may play a role in APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling and neurotransmission. Low density LRP also plays a role in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha-2-macroglobulin), and is involved in the local metabolism of complexes of plasminogen activators and their endogenous ligands. Low density LPR is postulated to be one of the major players in host resistance to HIV. The precursor low density LRP molecule is cleaved post-translationally to form a 85 kDa membrane-spanning subunit (LRP-85) and a 515 kDa large extracellular domain (LRP-515), which remains non-covalently associated with LRP-85. Following cleavage, the intracellular domain (LPRICD) is present in both the cytoplasm and the nucleus.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 4035
Alternate Names
  • FLJ16451
  • EC 3.4.21.9
  • LRP-1
  • EC 1.1.1.94
  • APR
  • CD91 antigen
  • APOER
  • type V tgf-beta receptor
  • Apolipoprotein E receptor
  • TbetaR-V/LRP-1/IGFBP-3 receptor
  • LRP
  • prolow-density lipoprotein receptor-related protein 1
  • CD91
  • A2MRTGFBR5
  • Alpha-2-macroglobulin receptorMGC88725
  • IGFBP3R
  • low density lipoprotein receptor-related protein 1

Research Areas for Low Density LRP

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Phospho-Specific

Bioinformatics Tool for Low Density LRP

Discover related pathways, diseases and genes to Low Density LRP. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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