Lamin C Products


Nuclear Lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A-type Lamins and B-type Lamins. The A-type Lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. Lamin A, Lamin C and Lamin Adel 10, while the B-type Lamins include two proteins arising from two distinct genes, i.e. Lamin B1 and Lamin B2. Recent evidence has revealed that mutations in A-type Lamins give rise to a range of rare but dominant genetic disorders, including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease and Dunnigan-type familial partial lipodystrophy. In addition, the expression of A-type Lamins coincides with cell differentiation and as A-type Lamins specifically interact with chromatin, a role in the regulation of differential gene expression has been suggested for A-type Lamins.


Product By Gene ID 4000
Alternate Names
  • renal carcinoma antigen NY-REN-32
  • CDDC
  • prelamin-A/C
  • CDCD1
  • lamin-A/C
  • PRO1,70 kDa lamin
  • progeria 1 (Hutchinson-Gilford type)
  • limb girdle muscular dystrophy 1B (autosomal dominant)
  • dilated 1A (autosomal dominant)
  • LGMD1B
  • LMNL1
  • FPLD
  • LMNC
  • EMD2
  • LFP
  • CMD1A
  • LDP1
  • lamin A/C-like 1
  • CMT2B1
  • lamin A/C

Bioinformatics Tool for Lamin C

Discover related pathways, diseases and genes to Lamin C. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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