IL-4 R alpha Products

Antibodies
Lysates
IL-4 R alpha Overexpression L ...
IL-4 R alpha Overexpression Lysate...
H00003566-T01
Species: Hu
Applications: WB
IL-4 R alpha Overexpression L ...
IL-4 R alpha Overexpression Lysate...
NBL1-11958
Applications: WB
Proteins
IL-4 R alpha Recombinant Prot ...
IL-4 R alpha Recombinant Protein
H00003566-G01
Species: Hu
IL-4 R alpha Partial Recombin ...
IL-4 R alpha Partial Recombinant P...
H00003566-Q01
Species: Hu
Applications: WB, ELISA, PA
IL-4 R alpha Recombinant Prot ...
IL-4 R alpha Recombinant Protein A...
NBP2-33592PEP
Species: Hu
Applications: AC
RNAi
IL-4 R alpha RNAi
IL-4 R alpha RNAi
H00003566-R04
Species: Hu
IL-4 R alpha RNAi
IL-4 R alpha RNAi
H00003566-R03
Species: Hu

Description

IL4 is a pleiotropic cytokine produced by activated T cells, mast cells and basophils. It is a ligand for Interleukin 4 receptor. The Interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. IL4 elicits many different biological responses, but has two dominant functions. The first is regulating differentiation of na ve CD4+ T cell to the Th2 type. Th2 cells produce IL4, IL5, IL10 and IL13, which tend to favor a humoral immune response while suppressing a cell mediated immune response controlled by Th1 cells. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. The second is regulating IgE and IgG1 production by B cells. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Product By Gene ID 3566
Alternate Names
  • IL-4 receptor subunit alpha
  • CD124 antigen
  • IL-4RA
  • interleukin-4 receptor subunit alpha
  • IL-4R-alpha
  • interleukin-4 receptor alpha chain
  • IL4RACD124
  • IL-4R subunit alpha
  • interleukin 4 receptor

Research Areas for IL-4 R alpha

Find related products by research area and learn more about each of the different research areas below.

Asthma
Cancer
Immunology

PTMs for IL-4 R alpha

Learn more about PTMs related to IL-4 R alpha.

Phosphorylation
Reduction
Citrullination
Methylation

Bioinformatics Tool for IL-4 R alpha

Discover related pathways, diseases and genes to IL-4 R alpha. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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