IL-10 R alpha Products

Antibodies
IL-10 R alpha Antibody (37607 ...
IL-10 R alpha Antibody (37607)
MAB274
Species: Hu
Applications: Neut
Host: Mouse Monoclonal
IL-10 R alpha Antibody [Uncon ...
IL-10 R alpha Antibody [Unconjugated]
AF-474-NA
Species: Mu
Applications: WB, Neut
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
IL-10 R alpha Antibody [Uncon ...
IL-10 R alpha Antibody [Unconjugated]
AF-274-NA
Species: Hu
Applications: WB, ICC, Neut
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Lysates
IL-10 R alpha Overexpression ...
IL-10 R alpha Overexpression Lysat...
NBL1-11896
Applications: WB
IL-10 R alpha Overexpression ...
IL-10 R alpha Overexpression Lysat...
H00003587-T01
Applications: WB
Proteins
IL-10 R alpha Recombinant Pro ...
IL-10 R alpha Recombinant Protein
NBP2-52077
Species: Hu
Applications: PAGE
IL-10 R alpha Recombinant Pro ...
IL-10 R alpha Recombinant Protein
H00003587-G01
Species: Hu
RNAi
IL-10 R alpha RNAi
IL-10 R alpha RNAi
H00003587-R02
Species: Hu

Description

The IL-10 receptor, IL-10R, is a member of the class II subgroup of the cytokine receptor family and exhibits structural similarity to the interferon receptor. IL-10R is expressed in B cells and T helper cells, as well as in LPS-induced mouse fibroblasts. Overall, mouse IL-10R and human IL-10R share 60% sequence identity at the protein level. Stimulation with IL-10 leads to tyrosine phosphorylation of JAK1 and Tyk2, but not JAK2 or JAK3. In addition to its role as an antagonist of IFN-gamma-mediated macrophage activation, IL-10Ralpha transmits differentiation as well as proliferative signals. IL-10R is constitutively expressed on human natural killer (NK) cells and the direct binding of IL-10 potentiates cytokine production by human NK cells.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Product By Gene ID 3587
Alternate Names
  • IL-10 receptor subunit alpha
  • IBD28
  • IL-10RA
  • CD210 antigen
  • IL-10R1
  • CDw210a
  • Interleukin-10 receptor subunit 1
  • interleukin-10 receptor subunit alpha
  • HIL-10R
  • interleukin-10 receptor alpha chain
  • CDW210A
  • IL10RIL-10R subunit alpha
  • IL-10R subunit 1
  • interleukin 10 receptor, alpha

PTMs for IL-10 R alpha

Learn more about PTMs related to IL-10 R alpha.

Phosphorylation

Bioinformatics Tool for IL-10 R alpha

Discover related pathways, diseases and genes to IL-10 R alpha. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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