IGF-I R Products

Antibodies
IGF-I R Antibody (3G5C1)
IGF-I R Antibody (3G5C1)
NB110-87052
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
Host: Mouse Monoclonal
IGF-I R Antibody (33255) [Unc ...
IGF-I R Antibody (33255) [Unconjug...
MAB391
Species: Hu
Applications: WB, ELISA(Cap), Neut
Host: Mouse Monoclonal
IGF-I R Antibody [Unconjugate ...
IGF-I R Antibody [Unconjugated]
AF-305-NA
Species: Hu, Mu
Applications: WB, IHC, ICC, Neut
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
ELISA Kits
Human IGF-I R ELISA Kit
Human IGF-I R ELISA Kit
KA2209
Species: Hu
Applications: ELISA
Lysates
IGF-I R Overexpression Lysate ...
IGF-I R Overexpression Lysate (Nat...
NBL1-11867
Applications: WB
IGF-I R Overexpression Lysate ...
IGF-I R Overexpression Lysate (Den...
H00003480-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human IGF-I R Pro ...
Recombinant Human IGF-I R Protein, CF
391-GR
Species: Hu
Applications: Bind
Recombinant Human IGF-I R (Hi ...
Recombinant Human IGF-I R (Histidi...
305-GR
Species: Hu
Applications: Bind
Recombinant Mouse IGF-I R Pro ...
Recombinant Mouse IGF-I R Protein
6630-GR
Species: Mu
Applications: BA
RNAi
IGF-I R RNAi
IGF-I R RNAi
H00003480-R04
Species: Hu
Applications: RNAi, RNAi SP

Description

The IGF1 receptor prefers IGF1 over IGF2 and weakly binds insulin. IGF1 receptor is a disulfide-linked heterotetrameric transmembrane protein consisting of two alpha (130 kD) and two beta (95 kD) subunits. Both the alpha and beta subunits are encoded within a single receptor precursor cDNA. The IGF1 receptor is therefore similar in structure to the insulin receptor. The proreceptor polypeptide is proteolytically cleaved and disulfide-linked to yield the mature heterotetrameric receptor. The IGF1 receptor is highly expressed in all cell types and tissues and is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival

Bioinformatics

Entrez Human
Mouse
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 3480
Alternate Names
  • IGF-I receptor
  • EC 2.7.10
  • Insulin-like growth factor I receptor
  • CD221 antigen
  • MGC18216
  • soluble IGF1R variant 2
  • JTK13
  • soluble IGF1R variant 1
  • IGFR
  • MGC142172
  • IGFIR
  • MGC142170
  • CD221
  • EC 2.7.10.1
  • insulin-like growth factor 1 receptor

Research Areas for IGF-I R

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Lipid and Metabolism
Neuroscience
Nutrient Sensing in the Brain
Phospho-Specific
Protein Kinase
Signal Transduction
Tyrosine Kinases

Bioinformatics Tool for IGF-I R

Discover related pathways, diseases and genes to IGF-I R. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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