IGF-I R Products

Antibodies
IGF-I R Antibody (33255) [Unc ...
IGF-I R Antibody (33255) [Unconjug...
MAB391
Species: Hu
Applications: WB, ELISA(Cap), Neut
Host: Mouse Monoclonal
IGF-I R Antibody (3G5C1)
IGF-I R Antibody (3G5C1)
NB110-87052
Species: Hu
Applications: WB, ELISA, Flow, IHC, IHC-P
Host: Mouse Monoclonal
ELISA Kits
IGF-I R ELISA Kit [Biotin]
IGF-I R ELISA Kit [Biotin]
KA2209
Species: Hu
Lysates
IGF-I R Overexpression Lysate ...
IGF-I R Overexpression Lysate (Nat...
NBL1-11867
Applications: WB
IGF-I R Overexpression Lysate ...
IGF-I R Overexpression Lysate (Den...
H00003480-T01
Applications: WB
Proteins
IGF-I R Peptide
IGF-I R Peptide
NBP1-77680PEP
Species: Hu
IGF-I R Recombinant Protein A ...
IGF-I R Recombinant Protein Antigen
NBP2-38543PEP
Species: Hu
Applications: AC
IGF-I R Recombinant Protein
IGF-I R Recombinant Protein
P4702
Species: Hu
Applications: Func, PAGE
RNAi
IGF-I R RNAi
IGF-I R RNAi
H00003480-R04
Species: Hu

Description

The IGF1 receptor prefers IGF1 over IGF2 and weakly binds insulin. IGF1 receptor is a disulfide-linked heterotetrameric transmembrane protein consisting of two alpha (130 kD) and two beta (95 kD) subunits. Both the alpha and beta subunits are encoded within a single receptor precursor cDNA. The IGF1 receptor is therefore similar in structure to the insulin receptor. The proreceptor polypeptide is proteolytically cleaved and disulfide-linked to yield the mature heterotetrameric receptor. The IGF1 receptor is highly expressed in all cell types and tissues and is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival

Bioinformatics

Entrez Human
Mouse
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 3480
Alternate Names
  • IGF-I receptor
  • EC 2.7.10
  • Insulin-like growth factor I receptor
  • CD221 antigen
  • MGC18216
  • soluble IGF1R variant 2
  • JTK13
  • soluble IGF1R variant 1
  • IGFR
  • MGC142172
  • IGFIR
  • MGC142170
  • CD221
  • EC 2.7.10.1
  • insulin-like growth factor 1 receptor

Research Areas for IGF-I R

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Lipid and Metabolism
Neuroscience
Nutrient Sensing in the Brain
Phospho-Specific
Protein Kinase
Signal Transduction
Tyrosine Kinases

Bioinformatics Tool for IGF-I R

Discover related pathways, diseases and genes to IGF-I R. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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