HPL-1 Products

Antibodies
HPL-1 Antibody
HPL-1 Antibody
38620002
Species: Ce
Applications: WB, ELISA, IHC, IHC-P
Host: Rabbit Polyclonal

Description

hpl-1 encodes one of two C. elegans heterochromatin protein 1 (HP1) homologs; loss of hpl-1 activity alone results in no obvious defects, but animals doubly mutant for hpl-1 and hpl-2 have defects in larval, somatic gonad and germline development; in addition, hpl-1 functions redundantly with hpl-2 and lin-13 in vulval development; rescuing HPL-1::GFP fusion proteins are expressed in nuclei throughout the life cycle, beginning at approximately the 50-cell stage of embryogenesis and continuing through larval and adult stages; expression is observed in most, but not all, cells and is particularly strong in head and tail hypodermal and neuronal nuclei; in nuclei, HPL-1::GFP is seen in foci that do not significantly overlap with those of HPL-2.

Bioinformatics

Entrez C. elegans
Alternate Names
  • HPL-1
  • HP1 Like (heterochromatin protein)