WB, ICC/IF, IHC, IHC-P, PEP-ELISAHost:
Applications: RNAi, RNAi SP
HRH2 encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.
Research Areas for Histamine H2 R
Find related products by research area and learn more about each of the different research areas below.GPCRStem Cell Markers
Bioinformatics Tool for Histamine H2 R
Discover related pathways, diseases and genes to Histamine H2 R. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.