HIP2 Products

Antibodies
HIP2 Antibody
HIP2 Antibody
NB300-840
Species: Hu
Applications: WB, IHC, IHC-P, PEP-ELISA
Host: Goat Polyclonal
HIP2 Antibody
HIP2 Antibody
NBP2-16831
Species: Hu, Mu
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
HIP2 Antibody
HIP2 Antibody
NBP1-91987
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
HIP2 Overexpression Lysate (N ...
HIP2 Overexpression Lysate (Native)
NBL1-17536
Applications: WB
Proteins
HIP2 Recombinant Protein Anti ...
HIP2 Recombinant Protein Antigen
NBP1-91987PEP
Species: Hu
Applications: AC
Recombinant Human HIP2 Protei ...
Recombinant Human HIP2 Protein
NBP1-50974
Species: Hu
Applications: PAGE
RNAi
HIP2 RNAi
HIP2 RNAi
H00003093-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The covalent attachment of ubiquitin to cellular proteins is catalyzed by members of a family of ubiquitin-conjugating enzymes, including UBC1 (E2). These enzymes participate in a variety of cellular processes, including selective protein degradation, DNA repair, cell cycle control, and sporulation (1). In this mechanism, the ATP-coupled activation and subsequent ligation of ubiquitin are catalyzed by separate enzymes (E1 and E3, respectively) functionally linked by ubiquitin carrier protein UBC1 (E2). Carrier protein has been proposed to constitute a family of isozymes having molecular masses of 14, 17, 20, 24, and 32 kDa whose role is to shuttle activated polypeptide in the form of a high-energy thiol ester intermediate to the carboxyl terminus of ubiquitin (2). The order of ubiquitin transfer is from E1 to E2, from E2 to E6-AP, and finally from E6-AP to a substrate (3).

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 3093
Alternate Names
  • Ubiquitin-protein ligase
  • ubiquitin-conjugating enzyme E2 K
  • Ubiquitin-conjugating enzyme E2-25K
  • Ubiquitin-conjugating enzyme E2-25 kDa
  • E2-25K
  • Ubiquitin-conjugating enzyme E2(25K)
  • E2(25K)
  • Ubiquitin carrier protein
  • DKFZp686J24237
  • Huntingtin-interacting protein 2
  • DKFZp564C1216
  • huntingtin interacting protein 2
  • EC 6.3.2.19
  • HYPG
  • HIP2LIG
  • HIP-2
  • ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)

Pathways for HIP2

View related products by pathway and learn more about each of the pathways below.

Cell Death
Pathogenesis
Conjugation
Cell Cycle
Protein Phosphorylation
Transport
S Phase
G1 Phase
Proteolysis
Localization
Autophagy

PTMs for HIP2

Learn more about PTMs related to HIP2.

Ubiquitination
Phosphorylation
Cleavage
Acetylation

Bioinformatics Tool for HIP2

Discover related pathways, diseases and genes to HIP2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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