GluR6/7 belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Kainate receptors are members of the lonotropic class of glutamate receptors and consist of GluR5-7 and KA1-2 subunits. Lonotropic receptors perform as excitatory neurotransmitters at various synapses in the central nervous system, and, once they bind to excitatory neurotransmitters a conformational change is initiated. This leads to the opening of the cation channel, thus converting the chemical signal to an electrical impulse. The subunit determined by GRIK2/3 is subject to RNA editing which may alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been defined for this gene.
|Product By Gene ID
- Glutamate receptor 7
- Excitatory amino acid receptor 5
- Glutamate receptor 6
- Excitatory amino acid receptor 4
Bioinformatics Tool for Glutamate Receptor 6/7
Discover related pathways, diseases and genes to Glutamate Receptor 6/7. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.