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Connexins, such as GJC3, are involved in the formation of gap junctions, intercellular conduits that directly connectthe cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of whichcontains 6 connexin subunits (Sohl et al., 2003 (PubMed 12881038)).(supplied by OMIM)