Gastrin peptide Products

Antibodies
Gastrin peptide Antibody
Gastrin peptide Antibody
NB100-91780
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Gastrin peptide Antibody
Gastrin peptide Antibody
NBP1-67574
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Gastrin peptide Antibody
Gastrin peptide Antibody
NB110-41549
Species: Hu, Rt(-)
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
Gastrin peptide Overexpressio ...
Gastrin peptide Overexpression Lys...
NBL1-10978
Applications: WB
Proteins
Gastrin peptide Recombinant P ...
Gastrin peptide Recombinant Protein
H00002520-P01
Species: Hu
Applications: WB, ELISA, PA

Description

Gastrin, which is normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets, is a hormone whose main function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. Gastrin also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. Gastrin is regulated by epidermal growth factor in both mice and humans. Gastrin is excreted in excess by pancreatic tumors in the Zollinger- Ellison syndrome. Gastrin maps to human chromosome 17q-21. Gastrin- Releasing Peptide (GRP) stimulates the release of gastrin as well as other gastrointestinal hormones, in addition to acting as an autocrine growth factor for certain cell types. High levels of GRP are found in the human lung just after birth and levels decrease thereafter in parallel with the observed disease in a number of pulmonary neuroendocrine cells. GRP is known to promote lung tumorigenesis in model systems and, interestingly, is induced by retinoic acid. GRP is involved in several functions with the hypothalamus, and is thought to play a role in regulating pituitary hormone secretion. GRP maps to human chromosome 18q21.

Bioinformatics

Entrez Human
Rat
Uniprot Human
Human
Human
Product By Gene ID 2520
Alternate Names
  • GAS
  • gastrin

PTMs for Gastrin peptide

Learn more about PTMs related to Gastrin peptide.

Phosphorylation
Cleavage
Amidation
Oxidation

Bioinformatics Tool for Gastrin peptide

Discover related pathways, diseases and genes to Gastrin peptide. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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