GABA A R alpha 3 Products

Antibodies
GABA A R alpha 3 Antibody
GABA A R alpha 3 Antibody
Species: Hu, Mu, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
GABA A R alpha 3 Antibody
GABA A R alpha 3 Antibody
NB100-61096
Species: Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
GABA A R alpha 3 Antibody
GABA A R alpha 3 Antibody
NBP1-52391
Species: Hu, Mu, Rt, Bt, Bv, Eq, Ha, Mk, Pm, Rb, Canine, Chicken, Opossum
Applications: IHC-P
Host: Goat Polyclonal
Lysates
GABA A R alpha 3 Overexpressi ...
GABA A R alpha 3 Overexpression Ly...
NBL1-10916
Applications: WB
Proteins
GABA A R alpha 3 Recombinant ...
GABA A R alpha 3 Recombinant Protein
H00002556-P02
Species: Hu
Applications: WB, ELISA, PA
GABA A R alpha 3 Recombinant ...
GABA A R alpha 3 Recombinant Protein
H00002556-P01
Species: Hu
Applications: WB, ELISA, PA
GABA A R alpha 3 Recombinant ...
GABA A R alpha 3 Recombinant Prote...
NBP1-87499PEP
Species: Hu
Applications: AC
RNAi
GABA A R alpha 3 RNAi
GABA A R alpha 3 RNAi
H00002556-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and sub-stance abuse. The GABAA-R is a multimeric subunit complex. To date six alphas, four betas and four gammas, plus alternative splicing variants of some of these subunits, have been identified (Olsen and Tobin, 1990; Whiting et al., 1999; Ogris et al., 2004). Injection in oocytes or mammalian cell lines of cRNA coding for alpha- and beta-subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a gamma-subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different alpha-subunits of the receptor (McKernan et al., 2000; Mehta and Ticku, 1998; Ogris et al., 2004; P ltl et al., 2003).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Rat
Product By Gene ID 2556
Alternate Names
  • gamma-animobutyric acid (GABA) A receptor, alpha 3
  • gamma-aminobutyric acid receptor subunit alpha-3
  • MGC33793
  • GABA(A) receptor subunit alpha-3
  • gamma-aminobutyric acid (GABA) A receptor, alpha 3

PTMs for GABA A R alpha 3

Learn more about PTMs related to GABA A R alpha 3.

Cleavage

Bioinformatics Tool for GABA A R alpha 3

Discover related pathways, diseases and genes to GABA A R alpha 3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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