Estrogen Receptor Products


Description

Estrogen Receptor alpha is a 65 kDa protein and a member of the steroid family of nuclear receptors. Estrogen Receptor alpha is a ligand-activated transcription factor that, when bound to estrogen, induces a conformational change that allows dimerization and binding to estrogen response element sequences. When bound to DNA, Estrogen Receptor alpha can positively or negatively regulate gene transcription. Like other steroid hormone receptors, Estrogen Receptors are intracellular proteins. Estrogen Receptors play an important role in regulating mammary gland growth and differentiation. Breast tumors that are ER positive may also show a more favorable response to anti-estrogen therapies

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Product By Gene ID 2099
Alternate Names
  • estrogen receptor alpha delta 4*5,6,7*/654 isoform
  • ER
  • estrogen receptor alpha delta 4 +49 isoform
  • Nuclear receptor subfamily 3 group A member 1
  • estrogen receptor alpha delta 3*4,56,7*/819-2 isoform
  • Estradiol receptor
  • estrogen receptor
  • Era
  • ESRESRA
  • NR3A1DKFZp686N23123
  • ER-alpha
  • estrogen receptor 1

Research Areas for Estrogen Receptor

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Breast Cancer
Cancer
Cell Biology
Cell Cycle and Replication
Dendritic Cell Markers
GPCR
Neuroscience
Phospho-Specific
Signal Transduction
Transcription Factors and Regulators

PTMs for Estrogen Receptor

Learn more about PTMs related to Estrogen Receptor.

Methylation
Phosphorylation
Demethylation
Reduction
Hydroxylation
Cleavage
Acetylation
Oxidation
Ubiquitination

Bioinformatics Tool for Estrogen Receptor

Discover related pathways, diseases and genes to Estrogen Receptor. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related Estrogen Receptor Blog Posts

Check out the latest blog posts on Estrogen Receptor.
Cytokeratin 18 - A Intermediate Filament Cyotskeletal Component
Keratins, also called cytokeratins, are a family of filamentous structural proteins that form the intermediate filaments within epithelial cells. Keratins are differentially expressed depending on both the epithelial cell origin and degree of differen...    Read more.
Androgen Receptor: What Makes a Man?
Steroid receptors (SRs) are a superfamily of ligand-dependent nuclear transcription factors that activate responsive genes response to hormone. Androgen receptors (ARs) are found in a wide variety of tissues, including reproductive organs, central ner...    Read more.
Read more Estrogen Receptor related blogs.