EGF R/ErbB1 Products

Antibodies
EGF R/ErbB1 Antibody (1240C) ...
EGF R/ErbB1 Antibody (1240C) [Unco...
MAB8967
Species: Hu
Applications: WB, Simple Western, ICC
Host: Rabbit Monoclonal
EGF R/ErbB1 Antibody [Unconju ...
EGF R/ErbB1 Antibody [Unconjugated]
AF231
Species: Hu
Applications: WB, Flow, IP, ELISA(Cap)
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
EGF R/ErbB1 [p Tyr1173] Antib ...
EGF R/ErbB1 [p Tyr1173] Antibody [...
Species: Hu
Applications: WB, Simple Western, IHC, ICC, ICFlow
Host: Rabbit Polyclonal
ELISA Kits
EGF R/ErbB1 [p Ser1070] ELISA ...
EGF R/ErbB1 [p Ser1070] ELISA Kit ...
KA2153
Species: Hu, Mu, Rt
EGF R/ErbB1 [p Ser1070] ELISA ...
EGF R/ErbB1 [p Ser1070] ELISA Kit ...
KA2154
Species: Hu, Mu, Rt
EGF R/ErbB1 [p Tyr1086] ELISA ...
EGF R/ErbB1 [p Tyr1086] ELISA Kit ...
KA2160
Species: Hu
Lysates
EGF R/ErbB1 Overexpression Ly ...
EGF R/ErbB1 Overexpression Lysate ...
H00001956-T01
Species: Hu
Applications: WB
EGF R/ErbB1 Overexpression Ly ...
EGF R/ErbB1 Overexpression Lysate ...
NBP2-04608
Applications: WB
Proteins
EGF R/ErbB1 Recombinant Prote ...
EGF R/ErbB1 Recombinant Protein An...
NBP2-52953PEP
Species: Hu
Applications: AC
EGF R/ErbB1 Recombinant Prote ...
EGF R/ErbB1 Recombinant Protein An...
NBP2-52952PEP
Species: Hu
Applications: AC
EGF R/ErbB1 Recombinant Prote ...
EGF R/ErbB1 Recombinant Protein An...
NBP1-84814PEP
Species: Hu
Applications: AC
RNAi
EGF R/ErbB1 RNAi
EGF R/ErbB1 RNAi
H00001956-R15
Species: Hu
EGF R/ErbB1 RNAi
EGF R/ErbB1 RNAi
H00001956-R13
Species: Hu
EGF R/ErbB1 RNAi
EGF R/ErbB1 RNAi
H00001956-R16
Species: Hu

Description

Epidermal growth factor receptor (EGFR) is a 170 kDa transmembrane glycoprotein receptor tyrosine kinase that, activated by epidermal growth factor (EGF), affects cell growth and differentiation (1). Binding of EGF or TGF alpha to EGFR activates tyrosine kinase activity of the receptor (2). The carboxy terminal tyrosine residues on EGFR, Tyr 1068, Tyr 1148, and Tyr 1173, are the major sites of autophosphorylation, which occurs as a result of EGF binding (3). Once activated, EGFR phosphotyrosines Y-1068 and Y-1173 mediate the binding of Grb2 to the EGFR. Addtionally, phosphotyrosine Y-1173 is a major binding site for SHC on the EGFR (4).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 1956
Alternate Names
  • ErbB1
  • HER1
  • EC 2.7.10
  • ERBB
  • mENA
  • epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog)
  • cell proliferation-inducing protein 61
  • EC 2.7.10.1
  • cell growth inhibiting protein 40
  • Receptor tyrosine-protein kinase erbB-1
  • avian erythroblastic leukemia viral (v-erb-b) oncogene homolog
  • Proto-oncogene c-ErbB-1
  • ERBB1PIG61
  • epidermal growth factor receptor

Research Areas for EGF R/ErbB1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Biology
Cell Cycle and Replication
Growth and Development
Hypoxia
Phospho-Specific
Signal Transduction
Tumor Suppressors
Tyrosine Kinases

Bioinformatics Tool for EGF R/ErbB1

Discover related pathways, diseases and genes to EGF R/ErbB1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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