cleaved p25 PARP Products

Antibodies
cleaved p25 PARP Antibody
cleaved p25 PARP Antibody
NBP1-71440
Species: Hu, Mu
Applications: WB, ELISA
Host: Rabbit Polyclonal

Description

Poly (ADP-ribose) polymerase (PARP) is zinc-dependent DNA binding protein that recognizes DNA strand breaks and is presumed to play a role in DNA repair (1). As a marker for apoptosis, PARP is cleaved in vitro by many caspases, and in vivo by Caspase-3 (2,3). Existing as a 116 kDa nuclear protein, PARP is cleaved between amino acids Asp214 and Gly215 to yield two fragments of 29 kDa and 85 kDa (2,4).

Bioinformatics

Uniprot Human
Product By Gene ID 142
Alternate Names
  • NAD(+) ADP-ribosyltransferase 1
  • EC 2.4.2
  • ADPRT 1
  • poly(ADP-ribose) synthetase
  • PARP-1
  • poly(ADP-ribose) polymerase
  • Poly[ADP-ribose] synthase 1
  • poly(ADP-ribosyl)transferase
  • poly (ADP-ribose) polymerase family, member 1
  • poly [ADP-ribose] polymerase 1
  • ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)
  • PPOLpADPRT-1
  • ADPRTADP-ribosyltransferase NAD(+)
  • PARPADPRT1
  • EC 2.4.2.30
  • poly (ADP-ribose) polymerase 1

Research Areas for cleaved p25 PARP

Find related products by research area and learn more about each of the different research areas below.

Base Excision Repair
Cancer
Core ESC-Like Genes
DNA Repair
Hypoxia
Stem Cell Markers
Tumor Suppressors

Bioinformatics Tool for cleaved p25 PARP

Discover related pathways, diseases and genes to cleaved p25 PARP. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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