cleaved BAD Products

Antibodies
cleaved BAD Antibody
cleaved BAD Antibody
NB100-56602
Species: Hu
Applications: WB, Flow-IC
Host: Rabbit Polyclonal

Description

The function of Bad, a proapoptotic member of the Bcl-2 family, is regulated primarily by rapid changes in phosphorylation that modulate its protein-protein interactions and subcellular localization. Human Bad, which is 43 amino acids shorter than its mouse counterpart, is cleaved by a caspase upon exposure of Jurkat T cells to anti-FAS antibody, tumor necrosis factor alpha (TNF-alpha), or TRAIL. Moreover, a truncated form of human Bad lacking the N-terminal 28 amino acids is more potent than wild-type Bad in inducing apoptosis. Bad plays a novel and important role in maintaining the apoptotic phenotype in response to various apoptosis inducers.

Bioinformatics

Product By Gene ID 572
Alternate Names
  • Bcl2-L-8
  • BCL-X/BCL-2 binding protein
  • BBC6
  • Bcl-XL/Bcl-2-associated death promoter
  • BCL2-binding protein
  • Bcl-2-like protein 8
  • BCL2-binding component 6
  • Bcl-2-binding component 6
  • BCL2-antagonist of cell death protein
  • BBC2
  • BCL2L8bcl2-L-8
  • bcl2 antagonist of cell death
  • BCL2-associated agonist of cell death

Research Areas for cleaved BAD

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Tumor Suppressors

Bioinformatics Tool for cleaved BAD

Discover related pathways, diseases and genes to cleaved BAD. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.