CD34 Class III Products

Antibodies
CD34 Class III Antibody (SI16 ...
CD34 Class III Antibody (SI16-01)
NBP2-67399
Species: Hu, Mu, Rt, Ca
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Monoclonal

Description

The highly glycosylated 75-120 kD antigen CD34 is possibly an adhesion molecule with a putative role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is thought to have a role in presenting carbohydrate ligands to selectins. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C, suggesting a putative role in signal transduction. Two isoforms of CD34 have been reported to be generated by alternative splicing. CD34 is highly expressed on hematopoietic progenitors, as well as on endothelial cells, brain, and testis. Staining for CD34 has been used to measure angiogenesis, which reportedly predicts tumor recurrence.

Bioinformatics

Entrez Human
Product By Gene ID 947
Alternate Names
  • CD34 antigenhematopoietic progenitor cell antigen CD34
  • CD34 molecule

Research Areas for CD34 Class III

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer
Cellular Markers
Hematopoietic Stem Cell Markers
Mast Cell Markers
Mesenchymal Stem Cell Markers
Stem Cell Markers
Tumor Suppressors

Bioinformatics Tool for CD34 Class III

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