Catenin alpha 1/2 Products

Antibodies
Catenin alpha 1/2 Antibody
Catenin alpha 1/2 Antibody
NB100-91684
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal

Description

alpha E-catenin (also designated alpha-catenin; cadherin-associated protein, alpha 1, 102kDa; and CAP102) plays a role in E-cadherin mediated cell-cell adhesion by linking E-cadherin to the cytoskeleton via beta- or gamma-catenin and Actin. alpha E-catenin connects cell-density-dependent adherens junctions with the developmental hedgehog pathway and may provide a negative feedback loop controlling the size of developing cerebral cortex. It is abundant in neuroepithelial precursor cells in the developing cortical ventricular zone of the brain, with reduced expression in the cortical plate. alpha E-catenin-vinculin interactions play a role in the assembly of the apical junction complex in epithelia. Catenins generally are thought to work as connectors that anchor E-cadherin to the cytoskeletal Actin bundle through the cadherin cytoplasmic domain. Dysfunction of this adhesion complex causes dissociation of cancer cells from primary tumor nodules, and is thus considered a contributing factor to metastasis.

Bioinformatics

Entrez Human
Rat
Product By Gene ID 1495
Alternate Names
  • FLJ52416
  • Cadherin-associated protein
  • FLJ36832
  • catenin alpha-1
  • catenin (cadherin-associated protein), alpha 1 (102kD)
  • cadherin-associated protein
  • Renal carcinoma antigen NY-REN-13
  • alphaE-catenin
  • Alpha E-catenin
  • alpha-catenin
  • CAP102
  • alpha-E-catenin
  • catenin (cadherin-associated protein), alpha 1, 102kDa

Research Areas for Catenin alpha 1/2

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cellular Markers
Core ESC-Like Genes
Cytoskeleton Markers
Stem Cell Markers

PTMs for Catenin alpha 1/2

Learn more about PTMs related to Catenin alpha 1/2.

Phosphorylation
Methylation
Cleavage
Biotinylation
Dephosphorylation
Reduction
Phosphorothioation
Farnesylation
Deacetylation

Bioinformatics Tool for Catenin alpha 1/2

Discover related pathways, diseases and genes to Catenin alpha 1/2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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