Bak1/2 is encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
|Product By Gene ID
- pro-apoptotic protein BAK
- BCL2-like 7 protein
- Bcl-2-like protein 7
- Apoptosis regulator BAK
- BCL2L7bcl-2 homologous antagonist/killer
- BCL2-antagonist/killer 1
Research Areas for BAK1/2
Find related products by research area and learn more about each of the different research areas below.ApoptosisCancerTumor Suppressors
Bioinformatics Tool for BAK1/2
Discover related pathways, diseases and genes to BAK1/2. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.