Hu, Mu, RtApplications:
WB, ELISA, Flow, ICC/IF, IHC, IHC-PHost:
WB, Flow, ICC/IF, IHC, IHC-FrHost:
WB, Flow, IHC, CyTOF-readyHost:
RNAi, RNAi SP
CD274 encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
|Product By Gene ID
- programmed cell death 1 ligand 1
- CD274 antigenMGC142294
- PDL1PDCD1 ligand 1
- PD-L1B7 homolog 1
- Programmed death ligand 1
- CD274 molecule
Research Areas for B7-H1/PD-L1/CD274
Find related products by research area and learn more about each of the different research areas below.Signal Transduction
Bioinformatics Tool for B7-H1/PD-L1/CD274
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Related B7-H1/PD-L1/CD274 Blog Posts
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