Adenosine A1 R Products

Antibodies
Adenosine A1 R Antibody
Adenosine A1 R Antibody
NB300-549
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Adenosine A1 R Antibody
Adenosine A1 R Antibody
NBP2-58443
Species: Hu
Applications: ICC/IF
Host: Rabbit Polyclonal
Adenosine A1 R Antibody
Adenosine A1 R Antibody
NBP1-00149
Species: Hu, Mu, Rt, Bv, Ca
Applications: PEP-ELISA
Host: Goat Polyclonal
Proteins
Adenosine A1 R Recombinant Pr ...
Adenosine A1 R Recombinant Protein...
NBP2-58443PEP
Species: Hu
Applications: B/N, Ctrl
RNAi
Adenosine A1 R RNAi
Adenosine A1 R RNAi
H00000134-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Adenosine receptors (ARs) are members of the 7-transmembrane domain G-protein-coupled receptor superfamily. Structural, biochemical and pharmacological analyses of the AR genes and protein has led to the discovery of four distinct AR subtypes (A1, A2a, A2b, A3). Activation of ARs mediates several receptor subtype-specific physiological processes that include cardiac rate, smooth muscle tone, platelet aggregation, inflammation, cell growth and death, and neurotransmission.The A1AR is a glycoprotein that can activate Gi and Go proteins in vitro. In intact cells, agonist occupation of the A1AR has been shown to cause pertussis toxin-sensitive inhibition of adenylyl cyclase activity and, in some systems, a stimulation of phospholipase C resulting in mobilization of intracellular calcium stores. Activation of potassium channels by A1AR has been intensively studied in relation to its dramatic effects on the cardiovascular system. A1AR protein is highly expressed in brain (especially cerebellum, hippocampus, thalamus, and cortex) and spinal cord and in part, modulates neurotransmitter release. In white adipocytes A1AR inhibits lipolysis and stimulates glucose uptake. Other tissues also express A1AR including kidney and testis.

Bioinformatics

Entrez Human
Rat
Uniprot Human
Human
Rat
Product By Gene ID 134
Alternate Names
  • ADORA 1
  • RDC7adenosine receptor A1
  • adenosine A1 receptor

Pathways for Adenosine A1 R

View related products by pathway and learn more about each of the pathways below.

Pathogenesis
Localization
Vasodilation
Smooth Muscle Contraction
Reverse Transcription
Cell Cycle
Aging
Muscle Contraction
Penile Erection
Cell Cycle Arrest

Research Areas for Adenosine A1 R

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
GPCR
Growth and Development
Immunology
Innate Immunity
Neuronal Cell Markers
Signal Transduction
Vision

PTMs for Adenosine A1 R

Learn more about PTMs related to Adenosine A1 R.

Phosphorylation

Bioinformatics Tool for Adenosine A1 R

Discover related pathways, diseases and genes to Adenosine A1 R. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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