Caspase 8 (CASP8) is a member of the cysteine-aspartic acid protease (caspase) family that is involved in the execution-phase of cell apoptosis. The sequential activation of caspases plays a central role in the execution-phase of cell apoptosis, and Caspase 8 is the most upstream protease in the the caspase activation cascade.
Caspase 8 is expressed as an inactive proenzyme which then undergos proteolytic processing by upstream caspases, to form an active (cleaved) caspase 8 form.
Caspase 8 antibodies are important tools for apoptosis studies and research on the caspase family mediated apoptosis signaling pathway.
|Product By Gene ID
- spinal and bulbar muscular atrophy
- Dihydrotestosterone receptorHYSP1
- Nuclear receptor subfamily 3 group C member 4
- androgen receptor
Bioinformatics Tool for active/cleaved Caspase 8
Discover related pathways, diseases and genes to active/cleaved Caspase 8. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.