Vision

Vision Infographic: Do you see how I see?

Vision involves several parts of the eye processing light which send signals to the brain via the optic nerve to process information. Learn more about the vision process and related ocular proteins in the infographic below.

 

Novus Biologicals offers research reagents mentioned in this infographic including:

RPE65: Vision, Blindness and Hope

Retinal pigment epithelium-specific 65 kDa protein (RPE65) is an essential vision protein, and so mutations in the RPE65 gene cause blindness. However, clinical trials using gene therapy to treat patients with a defective RPE65 gene suggest that some vision may be restored.

"I can see clearly now": Targeting Bestrophin 1 to treat Bestrophinopathies

Encoded by the VMD2 gene on chromosome 11q13 Bestrophin 1 is the prototypic member of the RFP family of proteins which are more commonly called "bestrophins". The protein family was originally identified in Caenorhabditis elegans based on a conserved amino acid motifs Arg-Phe-Pro (RFP). In humans there are four members of the bestrophin family numbered sequentially BEST1, BEST2, BEST3 and BEST4.

Vimentin Antibodies in Rheumatoid Arthritis & Cataracts Research

Vimentin is a 57kDa type III intermediate filament (IF) protein that is the major cytoskeletal component of mesenchymal cells and the first to be expressed during cell differentiation. It plays a significant role in supporting and anchoring the position of the organelles in the cytosol and its dynamic nature is important for cell flexibility.  It is responsible for maintaining cell shape and cytoplasm integrity.

Can Tubby Make You Tubby?

The TUB gene, which encodes for the protein Tubby, is evolutionarily conserved in human, chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito, C. elegans, and rice.

The Sox2 Antibody Aids Brain Cancer Research

The Sox2 antibody is widely used in sensory, neuroscience and stem cell marker research. Recently, Sox2 antibody preparations identified the Sox2 protein as a marker for malignant neural gliomas. We at Novus Biologicals offer a wide variety of highly validated Sox2 antibodies.

"Freeze!" - Arrestin Antibodies Used in New Serotonin Syndrome Study

The beta-arrestin family regulate receptor binding of G-proteins, a group of seven transmembrane receptor proteins which includes the adrenergic, dopamine and serotonin receptors. Recently, arrestin antibodies were used in a study into Serotonin Syndrome, a hallucinogenic disorder which can follow SSRI (selective serotonin reuptake inhibitor) use.