Blogs for July 2020

Tiny Antibodies (VHHs) from Llama Neutralize Respiratory Coronaviruses

Tuesday, July 14, 2020 - 14:10
Sharks and llamas produce smaller antibodies called heavy chain-only antibodies (HCAbs) with a single variable domain, VHH.

By Jamshed Arslan, Pharm. D., PhD.

VHH Single Domain Antibodies vs Conventional Antibodies

The immune system protects living organisms against harmful substances. B cells ward off infections by producing antibodies to invading pathogens. Conventional antibodies are stable only at a narrow range of temperature and pH. They are also too big to penetrate tissues or to bind with many active sites on proteins. Thankfully, sharks and camelids like llamas...


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