Novus Biologicals launches a new Sulfatase 2 antibody

Novus Biologicals released a new antibody to Sulfatase 2 this past week.  This Sulfatase 2 antibody (catalog number NBP1-36727) has been tested by Western blot analysis on MCF7 conditioned media and by immunohistochemical analysis on non-small-cell lung carcinoma.  It also cross-reacts with human and mouse, and is useful for immunoprecipitation and ELISA.

Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines, and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as Sulfatase 2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai, et al., 2005, PMID: 16192265). Sulfatase 2 is highly expressed in the ovary, skeletal muscle, stomach, brain, uterus, heart, kidney and placenta.

Based on bioinformatics data from our Novus Explorer too, Sulfatase 2 is related to Sulfatase 1, FGF2, VEGFA, MAP3K14, Syndecan 1 and Syndecan 2.  For more information on this new Sulfatase 2 antibody, view the product datasheet.   Novus Biologicals offers it in a 0.1mL size, and also a 25uL sample size.


For more information on this new Sulfatase 2 antibody or to inquire about product collaborations, please contact the Novus Product Development Team by calling 303-730-1950 or via e-mail at

Release Date: 
Friday, April 9, 2010 - 06:00