Novus Biologicals Announces LIPA Antibody made using SDIX Genomic Antibodiesâ„¢

Novus Biologicals announced today a new LIPA Antibody (NBP1-54155) for use as a liver and kidney marker in cholesterol metabolism research.  This LIPA antibody was made using SDIX Genomic Antibody TechnologyTM (GATTM). 

Lipase A (LIPA), also known as cholesterol ester hydrolase, is a critical enzyme for metabolism, sequestration and degradation of cholesterol. Specifically, LIPA is responsible for the intracellular hydrolysis of cholesteryl esters and triglycerides.

Mutations in LIPA can result in lipoprotein cholesterol accumulation leading to atherosclerosis, inflammation, Type 2 diabetes and chronic kidney disease. For instance, in Wolman disease, a deficiency of LIPA causes a toxic buildup of cholesterol in spleen, liver, bone marrow, intestine, adrenal glands and lymph nodes.

The LIPA Antibody (NBP1-54155) has been validated for use in Western blot and fluorescent immunostaining of human and mouse samples. Therefore, this antibody will serve as a helpful tool for a variety of research on cholesterol regulation.

SDIX GAT uses sophisticated bioinformatics and immunization strategies to produce high-quality antibodies that specifically bind to targeted regions of the protein in its naturally folded form. The ability of an antibody to recognize a protein’s naturally folded state enables its utility in high-value applications like sandwich immunoassay, ChIP and flow cytometry.  Learn more about SDIX Genomic Antibodiesâ„¢ by reading the SDIX Genomic Antibodies FAQ or by downloading the SDIX Genomic Antibodies White Paper.

About Novus Biologicals (

Novus Biologicals is a biotechnology company whose mission is to accelerate scientific discovery by developing and marketing unique products in the forefront of science.  Novus Biologicals provides primary antibodies, secondary antibodies, conjugated antibodies, proteins, peptides, isotype and loading controls, RNAi, lysates, stem cell lines and antibody labeling kits to the bioscience community.  All of Novus' products are 100% guaranteed to work in the species and applications listed on the datasheet.  By serving niche and emerging markets, Novus Biologicals has formed and will continue to form ongoing partnerships with leading researchers.

About SDIX (

SDIX is a biotechnology company with a core expertise in creating better antigens, better antibodies and better assays for the pharmaceutical, biotechnology and food safety markets. For over 20 years, SDIX has been a leading immuno-solutions company, developing results-oriented and innovative antibody-based solutions that enable customers to meet high performance research, diagnostic and commercialization objectives.

In the life science market, SDIX’s technology and capabilities are being used to help discover disease mechanisms, facilitate development of new drugs and provide antibodies and assays for the diagnosis of disease.  In the food safety market, SDIX continues to expand its footprint as an international supplier of rapid pathogen test technologies that enable more accurate and cost-effective results.

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Release Date: 
Tuesday, May 31, 2011 - 06:00