New Group of EpiPlus Histone Modification Antibodies Released

Novus Biologicals announced today the release of a new group of Epi-PlusTM antibodies for histone modification testing. Over the past several months, Novus has collaborated with 21st Century Biochemicals, a leading manufacturer of custom antibodies and peptides, to generate the most well validated antibodies for modified histones and other epigenetic targets.   

Histone modifications are part of a complicated system of checks and balances at the epigenetic level and several histone modifications have been definitively shown to affect the regulation of transcription in a variety of cellular processes.

The laboratory teams at both Novus and 21st Century have performed extensive validation work in multiple assays, including chromatin immunoprecipitation (ChIP), Western Blot, dot blots using modified peptide arrays, and immunocytochemistry (ICC).  Additionally, our lab team is in the process of characterizing the entire Epi-PlusTM line in C. elegans lysates, with data coming in the next few months. Therefore, you can be assured that all Epi-PlusTM antibodies have been extensively characterized and validated, and are of the highest quality compared to other similarly commercially available products.

The complete list of currently available Epi-PlusTM antibodies is available here, with the newly added antibodies:

·         Histone H3.2 K9Me2 pT6 Antibody (cat # NB21-1053)

·         Histone H3.2 pS10 Antibody (cat # NB21-1091)

·         Histone H3.2 K4Me1 Antibody (cat # NB21-1021)

·         Histone H3.2 K9Ac Antibody (cat # NB21-1074)

·         Histone H3.2 R2Me1 Antibody (cat # NB21-1001)

·         Histone H4 R3Me1 Antibody (cat # NB21-2011)

·         Histone H3.2 R8Me2s Antibody (cat # NB21-1063)

Over the next few months, Novus will be releasing additional antibodies for the Epi-PlusTM product line, including:

·         Histone H3.2 K18Me3

·         Histone H3.2 K36Ac

·         Histone H3.2 R2Me2a

·         Histone H3.2 K18Me1

·         Histone H3.2 pS1

·         Histone H3.2 K5Ac

·         Histone H3.2 K79Me1

·         Histone H3.2 K12Ac

Novus also offers a Histone Modification Map poster for quick and easy reference of the important epigenetic modification sites. Sign up here to request complimentary posters, catalogs and more.

About Novus Biologicals (

Novus Biologicals is a biotechnology company whose mission is to accelerate scientific discovery by developing and marketing unique products in the forefront of science.  Novus Biologicals provides primary antibodies, secondary antibodies, conjugated antibodies, proteins, peptides, isotype and loading controls, RNAi, lysates, stem cell lines and antibody labeling kits to the bioscience community.  All of Novus' products are 100% guaranteed to work in the species and applications listed on the datasheet.  By serving niche and emerging markets, Novus Biologicals has formed and will continue to form ongoing partnerships with leading researchers.

About 21st Century Biochemicals (

21st Century Biochemicals provides solutions for biomedical researchers worldwide ranging from the manufacture of polyclonal and monoclonal antibodies to custom and bioactive peptides, arrays, libraries and peptidomimetics.  Consisting of a core of PhD scientists with decades of experience, 21st Century Biochemicals provides peptide and antibody solutions with the most rigorous peptide QC in the industry:  nanospray MS and HPLC analysis as well as CID MS/MS peptide sequence confirmation.    100% of the peptides and antibodies provided by 21st Century Biochemicals are manufactured in their facility outside of Boston, MA, providing unmatched product quality and consistency.

Release Date: 
Tuesday, September 27, 2011 - 06:00