xCT Antibody (NB300-318B)
xCT Antibody [Biotin]
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anti-Amino acid transport system xc xCT antibody, anti-XCT antibody, anti-SLC7A11 antibody, anti-Cysteine/glutamate transporter antibody, anti-xCT antibody, anti-Solute Carrier Family 7 antibody, anti-SLC7a11 antibody, anti-Member 11 (SCL7a11) antibody, anti-cystine/glutamate transporter antibody, anti-CCBR1 antibody, anti-Calcium channel blocker resistance protein CCBR1 antibody, anti-Amino acid transport system xc-xCT antibody, |
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xCT Antibody [Biotin] Summary: | | Gene: | SLC7A11 |
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| Purity: | Immunogen affinity purified |
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| Host: | Rabbit |
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| | Specificity: | This is specific for XCT. |
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| Publications: | Antibody has been mentioned in at least 1 Publication. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional xCT Products xCT Antibody [Biotin] Details: | Conjugate: | Biotin |
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| Immunogen: | A synthetic peptide made to a region within the N-terminus of the human XCT protein sequence (between residues 1-50). |
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This antibody reacts with the human and mouse proteins. Other species have not been tested. |
| Uses: | By Western blot a band at ~55 kDa is seen. Immunoprecipitation is not recommended. |
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| Dilutions: | Immunohistochemistry-Paraffin,
Western Blot 1:1000 |
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| Unit Size: | 0.1 ml |
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| Concentration: | 1.0 mg/ml |
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| Positive Controls: | 2 Positive Controls |
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| Conjugated Antibodies: | 1 Conjugated Antibodies |
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Packaging: | Storage: | Store at 4 °C. Do not freeze. |
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| Buffer: | PBS |
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| Preservative: | No Preservative |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: Mammalian amino acid transport systems consist of a large variety of transporters. The amino acid transporter, cystine/glutamic acid transporter xCT, for system xc has been proposed to be responsible for the cystine transport through the plasma membrane. System xc mediates an amino acid exchange and prefers cystine and glutamate as its substrates. The transporter designated as xCT requires 4F2 heavy chain (4F2hc:CD98) for its functional expression, and belongs to the family of amino acid transporters that associates with the type II membrane glycoproteins such as 4F2hc. In brain, it has been proposed that system xc is up-regulated in glial cells upon oxidative stress and plays an essential roles to protect neurons against oxidative stress. Recent studies have implicated xCT as a gateway that Kaposi's sarcoma herpesvirus (KSHV) uses to enter cells.
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Reviews (0) Related Products (25) Exploring xCT Working with xCT
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Working with xCT
xCT Antibody [Biotin] Images (0)
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Publications (1)xCT Antibody [Biotin] Product Specific:- Liu, R., et al. Cystine-Glutamate Transporter SLC7A11 Mediates Resistance to Geldanamycin, but Not to 17-(Allylamino)-17-demethoxygeldanamycin. Mol. Pharmacol., Dec 2007;72:1637-1646.
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Jump to: Conjugated Antibodies, Positive Controls, Antibody Packs, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsConjugated AntibodiesPositive ControlsAntibody Packs (1)Lysates (1)Peptides and ProteinsPrimary Antibodies (20)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| xCT Antibody | NB300-318 | Hu, Mu | ICC, IF, IHC-P, WB | (3) | (2) | | | | xCT Antibody | NB300-317 | Ca, Hu, Mu, Rt | WB | (1) | (1) | | | | xCT Antibody | NB100-59735 | Ca, Hu | PEP-ELISA | (1) | (1) | | | | xCT Antibody | PAB12027 | Hu, Mu | IHC-P, WB | | | | | | xCT Antibody | PAB15950 | Mu, Rt | ELISA, WB | | | | | | ... and 15 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Rabbit IgG Antibody [HRP] | NB730-H | Rb | ELISA, ICC, IHC-P, WB | | (5) | | | | Rabbit IgG Antibody [FITC] | NB730-F | Rb | ICC, IHC-P | | (1) | | | | Rabbit IgG Antibody [Biotin] | NB730-B | Rb | ELISA, ICC, IHC-P, WB | | | | | | Rabbit IgG, H/L Chains Antibody [DyLight 488] | NBP1-72944 | Rb | FLISA, IF, WB | (3) | | | | | Rabbit IgG Antibody [Alkaline Phosphatase] | NB730-AP | Rb | ELISA, ICC, IHC-P, WB | | (1) | | | | See All » |
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