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Publications for xCT (1)
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| Publication |
Applications |
Species |
| Zhang W, Trachootham D, Liu J, Chen G, Pelicano H, Garcia-Prieto C, Lu W, Burger JA, Croce CM, Plunkett W, Keating MJ, Huang P. Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia. Nat Cell Biol;14(3):276-86. 2012 Feb 19. [PMID: 22344033] |
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FAQs for xCT (0)
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Bioinformatics Tool for xCT
Discover related pathways, diseases and genes to xCT. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Diseases for xCT
Discover more about diseases related to xCT.
- Malignant Neoplasms
- Neoplasms
- Glioma
- Nerve Degeneration
- Nervousness
- Brain Neoplasms
- Hyperplasia
- Neurodegenerative Disorders
- Parkinson Disease
- Fracture
- Alzheimer's Disease
- Kaposi Sarcoma
- Sarcoma
- Neurotoxicity Syndromes
- Neoplasm Metastasis
- Atrophy
- Osteopenia
- Carcinoma
- Malignant Neoplasm Of Breast
- Cerebral Atrophy
Pathways for xCT
View related products by pathway.
- Transport
- Cell Death
- Amino Acid Transport
- Cell Proliferation
- Pathogenesis
- Secretion
- Neuroprotection
- Localization
- Cell Growth
- Cell Cycle
- Aging
- Glutamate Homeostasis
- L-cystine Transport
- Cell Cycle Arrest
- Ossification
- Segmentation
- Cell-cell Adhesion
- Programmed Cell Death
- Pigmentation
- Reverse Transcription
Research Areas for xCT
Find related products by research area.
PTMs for xCT
Learn more about PTMs related to xCT.
- Phosphorylation
- Reduction
- Biotinylation
- Carboxylation
- Oxidation
- Cleavage
- Dephosphorylation
- Methylation
- Ubiquitination
Blogs on xCT
Check out the latest blog posts on xCT.
xCT: Friend or Foe?
There are two opposing sides to the controversial cysteine/glutamate antiporter. On one hand, it can be viewed a guardian of the cell, protecting it from the damaging oxidative stress that can cause cell death and even cancer. But, conversely, it has ... Read full blog post.
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Glutathione and xCT: Chemoresistance in Tumor Cells
Glutathione, called GSH in its reduced form and GSSG or L(-)-Glutathione in its oxidized form, is an endogenous antioxidant found in most cells in the body. Glutathione's functions include detoxifying xenobiotics from the body, assisting in Read full blog post.
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![Western Blot: xCT Antibody [NB100-59735] - (0.02ug/ml) staining of Human Spleen lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.](http://images.novusbio.com/fullsize/xCT Antibody-Western Blot-NB100-59735-img0001.jpg)
![Western Blot: xCT Antibody [NB100-59735] (0.02ug/ml) staining of Human Spleen lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.](http://images.novusbio.com/fullsize2/xCT Antibody-Western Blot-NB100-59735-img0002.jpg)
)-Western Blot-NBP1-71754-img0003.jpg "Western Blot: CD98 Antibody (EPR3548(2)) [NBP1-71754] - (A) HeLa, (B) HepG2, (C) Raji, and (D) Molt-4 cell lysates.")
)-Immunohistochemistry-Paraffin-NBP1-71754-img0004.jpg "Immunohistochemistry-Paraffin: CD98 Antibody (EPR3548(2)) [NBP1-71754] Human testis tissue.")
-Western Blot-NB100-80011-img0003.jpg "Western Blot: Nrf2 Antibody (EP1808Y) [NB100-80011] HepG2 cell lysate using a 1:2000 dilution.")
-Immunohistochemistry-NB100-80011-img0002.jpg "Immunohistochemistry: Nrf2 Antibody (EP1808Y) [NB100-80011] - Immunohistochemical analysis of paraffin-embedded human lung adenocarcinoma using anti-Nrf2 Antibody.")
-Western Blot-NB110-58775-img0004.jpg "Western Blot: GLT1b Antibody (10B7) [NB110-58775] - Specifically recognizes GLT1b on a western blot. Lanes A and B represent COS7 cells transfected with GLT1a and GLT1b, respectively. The ~ 70kDa band is the expected size.")
-Immunocytochemistry-Immunofluorescence-NB110-58775-img0005.jpg "Immunocytochemistry/Immunofluorescence: GLT1b Antibody (10B7) [NB110-58775] - Immunocytochemistry on COS7 cells transfected with GLT1b using GLT1b monoclonal antibody.")
-Western Blot-NBP1-47416-img0003.jpg "Western Blot: GABPA Antibody (8C1B10) [NBP1-47416] - Western blot analysis using GABPA mouse mAb against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY GABPA cDNA (2).")
-Western Blot-NBP1-47416-img0002.jpg "Western Blot: GABPA Antibody (8C1B10) [NBP1-47416] - Western blot analysis using anti-GABPA monoclonal antibody against Hela (1), A549 (2), MCF-7 (3), NIH/3T3 (4) and SMMC-7721 (5) cell lysate.")
-Western Blot-NB300-164-img0003.jpg "Western Blot: Bestrophin 1 Antibody (E6-6) [NB300-164] - Detection of Bestrophin (68 kDa) from human RPE cell lysate.")
-Western Blot-NB110-55569-img0003.jpg "Western Blot: c-jun Antibody (E254) [NB110-55569] NIH3T3 cell lysate using a 1:2,000 dilution.")
-Immunohistochemistry-NB110-55569-img0002.jpg "Immunohistochemistry: c-jun Antibody (E254) [NB110-55569] - Immunohistochemical analysis of paraffin-embedded skin carcinoma using anti-c-Jun (N-term)")
-Western-Blot-NBP1-97507-img0002.jpg "Western Blot: Heme Oxygenase 1 Antibody (HO-1-1) [NBP1-97507] - Lane 1: MW marker; Lane 2: HO-1 (rat), (recombinant); Lane 3: HO-1 (human), (recombinant); Lane 4: HO-2 (human), (recombinant); Lane 5: MDBK cell lysate; Lane 6: Dog liver microsome; Lane 7: Mouse liver microsome.")
-Immunohistochemistry-Paraffin-NBP1-97507-img0001.jpg "Immunohistochemistry-Paraffin: Heme Oxygenase 1 Antibody (HO-1-1) [NBP1-97507] - Analysis of human spleen tissue stained with HO-1, mAb (HO-1-1) at 10ug/ml.")
-Western Blot-NBP1-47842-img0008.jpg "Western Blot: ERK2 Antibody (6E5) [NBP1-47842] Analysis of extracts (35ug) from 9 different cell lines by using anti-ERK2 monoclonal antibody.")
-Immunohistochemistry-Paraffin-NBP1-47842-img0007.jpg "Immunohistochemistry-Paraffin: ERK2 Antibody (6E5) [NBP1-47842] - Staining of paraffin-embedded pancreas tissue using anti-ERK2 mouse monoclonal antibody.")
)-Western Blot-NBP1-95921-img0003.jpg "Western Blot: EAAT3 Antibody (EPR6774(B)) [NBP1-95921] (A) fetal brain, (B) human testis, and (C) fetal muscle lysates.")
)-Immunohistochemistry-Paraffin-NBP1-95921-img0002.jpg "Immunohistochemistry-Paraffin: EAAT3 Antibody (EPR6774(B)) [NBP1-95921] - human kidney tissue using anti-EAAT3.")
