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Vimentin is an intermediate filament protein, expressed exclusively by mesenchymal cells. Along with actin microfilaments and tubulin microtubules, Vimentin is the third major constituent of the cytoskeleton. Therefore, Vimentin is critical for proper organell anchoring and cellular structure.

Vimentin antibodies are useful for cytoskeletal research and as mesenchymal cells.

Gene ID: 7431
FLJ36605 , vimentin

Vimentin as a Marker for Epithelial-to-Mesenchymal Transition

Epithelial-to-mesenchymal transition (EMT) is a critical event in the induction of cell motility and increased survival both under physiological situations like wound healing or development, as well as in malignant cells undergoing invasion and metastasis. Vimentin is ...
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Vimentin Antibodies in Rheumatoid Arthritis & Cataracts Research

Vimentin is a 57kDa type III intermediate filament (IF) protein that is the major cytoskeletal component of mesenchymal cells and the first to be expressed during cell differentiation. It plays a significant role in supporting and anchoring the position ...
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ZMPSTE24 Mutations, Lamin A Processing & Laminopathies

ZMPSTE24 (FACE-1, CAAX prenyl protease 1 homolog) is a membrane associated zinc metalloprotease of the peptidase M48A family. It's catalytic activity can be defined as the peptide bond hydrolyzed in the sequence -C-|-A-A-X in which C is an S-isoprenylated ...
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