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TNF alpha Products

TNF alpha Primary Antibodies

We have 63 TNF alpha Antibodies including 9 polyclonal and 54 monoclonal antibodies.

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TNF alpha Lysates

We have 1 TNF alpha Lysate.

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TNF alpha Peptides and Proteins

We have 20 TNF alpha Proteins.

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TNF alpha Antibody Pairs

We have 3 TNF alpha Antibody Pairs.

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TNF alpha ELISA Kits

We have 8 TNF alpha ELISA Kits.

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TNF alpha RNAi

We have 1 TNF alpha RNAi.

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Description

TNF-alpha (Tumor necrosis factor, alpha), a member of the TNF ligand superfamily, is among others, secreted by macrophages, activated monocytes, neutrophils, T-cells, B-cells and natural killer cells stimulated by bacterial lipopolysaccharides. TNF-alpha shows approximately 30% homology with TNF-beta. TNF-alpha plays an important role in the regulation of immune cells. TNF-alpha has many biological activities, including a cytotoxic effect to various tumor cells, causes inflammation, cellular proliferation and plays a critical role in mediating resistance to bacterial infections. Human and murine TNF-alpha show approximately 79% homology and human TNF-alpha is active on murine cells with a slightly reduced specific activity.

Bioinformatics

  • Entrez
  • Uniprot
  • Product By Gene ID7124
  • Alternate Names
    • tumor necrosis factor
    • APC1 protein
    • TNF-alphacachectin
    • TNFSF2TNF superfamily, member 2
    • TNFATNF, macrophage-derived
    • DIF
    • TNF, monocyte-derived
    • Tumor necrosis factor ligand superfamily member 2
    • tumor necrosis factor alpha
    • TNF-a
    • tumor necrosis factor-alpha
    • tumor necrosis factor (TNF superfamily, member 2)
    • Cachectin

Diseases related to TNF alpha

Discover more about diseases related to TNF alpha.

  • Inflammation
  • Malignant Neoplasms
  • Arthritis
  • Tissue Adhesions
  • Neoplasms
  • Rheumatoid Arthritis
  • Inflammatory Response
  • Systemic Infection
  • Infective Disorder
  • Autoimmune Reaction
  • Carcinoma
  • Diabetes Mellitus
  • Septic Shock
  • Leukemia
  • Autoimmune Diseases
  • Pneumonia
  • Nervousness
  • Obesity
  • Ischemia
  • Edema

Pathways for TNF alpha

View related products by pathway and learn more about each of the pathways below.

  • Secretion
  • Pathogenesis
  • Cytokine Production
  • Inflammatory Response
  • Immune Response
  • Cell Death
  • Cell Proliferation
  • Cell Adhesion
  • Cell Activation
  • Localization
  • Cytokine Secretion
  • Cell Growth
  • Phagocytosis
  • Angiogenesis
  • Bone Resorption
  • Transport
  • Hypersensitivity
  • Macrophage Activation
  • Sensitization
  • Cell Cycle

Research Areas for TNF alpha

Find related products by research area and learn more about each of the different research areas below.

PTMs for TNF alpha

Learn more about PTMs related to TNF alpha.

  • Phosphorylation
  • Cleavage
  • Oxidation
  • Reduction
  • Nitration
  • Glycosylation
  • Methylation
  • Ubiquitination
  • Acetylation
  • Dephosphorylation
  • Biotinylation
  • Phosphorothioation
  • Citrullination
  • Ribosylation
  • Acylation
  • Deacetylation
  • Myristoylation
  • Iodination
  • Nitrosylation
  • Demethylation

Bioinformatics Tool for TNF alpha

Discover related pathways, diseases and genes to TNF alpha. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.


 

Related TNF alpha Blog Posts

Check out the latest blog posts on TNF alpha.
CD11b: Marking a new B Cell type Responsible for Cell-Mediated Immunity
Still think B lymphocytes just produce antibodies? Think again! Although, B cells are vital for the humoral immune response, many studies in recent years have begun to uncover antibody-independent actions of B cells: regulating T cells and...    Read more.
Monocyte Chemoattractant Protein 1 in Immune System Response
MCP1, also known as CCL2, is a small chemokine factor belonging to the CC chemokine family. It is predominantly produced by endothelial cells and macrophages, and specifically is a chemoattractant for monocytes and basophils. It is produce...    Read more.
"Get the skinny" on Adiponectin & Leptin Antibodies
We at Novus Biologicals have an extensive antibody catalog covering lipid and metabolism research, including Adiponectin and leptin antibody products. Excess body fat is linked to many human diseases, including IRS (insulin resistance s...    Read more.

Read more TNF alpha related blogs.