TLR5 Products

Primary Antibodies

Peptides and Proteins

TLR5 Partial Recombinant Protein
H00007100-Q01
Species Reactivity: Human
Applications: WB, ELISA, PA


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TLR5 Recombinant Protein
H00007100-Q03
Species Reactivity: Human
Applications: WB, ELISA, PA


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TLR5 Peptide
NBP1-76662PEP
Species Reactivity: Human
Applications: B/N


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RNAi

TLR5 RNAi
H00007100-R02
Species Reactivity: Human


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Reporter Cell Lines

Description

The Toll like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans. The TRL family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLRs characterized so far activate the MyD88/interleukin 1 receptor-associated kinase (IRAK) signaling pathway. Toll-like receptor 5 (TLR5) expression is upregulated following exposure to bacteria or to the TLR5 agonist, flagellin. Gram-negative bacteria, stimulate monocyte/macrophage cells in a TLR5-specific, CD14-independent manner. The TLR5 receptor thus appears to be the principal means by which the innate immune system recognizes flagellated bacterial pathogens.

Bioinformatics

  • Entrez
  • Uniprot
  • Product By Gene ID7100
  • Alternate Names
    • MGC126430
    • MGC126431
    • SLEB1FLJ10052
    • TIL3Toll/interleukin-1 receptor-like protein 3
    • toll-like receptor 5

Bioinformatics Tool for TLR5

Discover related pathways, diseases and genes to TLR5. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.