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TLR5 Products
TLR5 Primary Antibodies

21 TLR5 Antibodies including 8 polyclonal and 13 monoclonal antibodies. (view)

TLR5 Lysates

View our TLR5 Lysate. (view)

TLR5 Peptides and Proteins

4 TLR5 Proteins. (view)

TLR5 RNAi

View our TLR5 RNAi. (view)

The Toll like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans. The TRL family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLRs characterized so far activate the MyD88/interleukin 1 receptor-associated kinase (IRAK) signaling pathway. Toll-like receptor 5 (TLR5) expression is upregulated following exposure to bacteria or to the TLR5 agonist, flagellin. Gram-negative bacteria, stimulate monocyte/macrophage cells in a TLR5-specific, CD14-independent manner. The TLR5 receptor thus appears to be the principal means by which the innate immune system recognizes flagellated bacterial pathogens.

Gene ID: 7100
Related Pathways, Diseases and Genes to TLR5
(see alternate names)
MGC126430 , MGC126431 , SLEB1FLJ10052 , TIL3Toll/interleukin-1 receptor-like protein 3 sli, toll-like receptor 5