TIM-2 Products

TIM-2 Antibodies

AF1885
    TIM‑2  was detected in perfusion fixed frozen sections of mouse liver using Goat  Anti-Mouse TIM‑2 Antigen Affinity-purified Polyclonal Antibody  (Catalog # AF1885) at 1.7 µg/mL for 1 hour at room  temperature followed by incubation with the Anti-Goat IgG VisUCyte™  HRP Polymer Antibody (Catalog # <a class=
Species: Mouse
Applications: WB, IHC
Host: Goat Polyclonal
MAB1885
Species: Mouse
Applications: WB
Host: Rat Monoclonal
BAF1885
Species: Mouse
Applications: WB
Host: Goat Polyclonal

Description

Tim-2 is a transmembrane protein known as T cell immunoglobulin and mucin domain containing protein-2. It is expressed on activated T cells and preferentially on differentiated Th2 cells. Sema4A is the ligand of Tim-2. A blockade of Tim-2/Tim-2 ligand interaction results in T cell hyperproliferation and Th2 cytokine production. Tim-2 plays a critical role in the development of atopic disease and other Th2-biased immune responses.

Bioinformatics

Entrez Mouse
Alternate Names
  • Tim2
  • T Cell immunoglobulin and mucin domain protein 2
  • Tim2
  • T Cell immunoglobulin and mucin domain protein 2