TGF-beta RI/ALK-5 Products

Description

TGF beta Receptor I is encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS).

Bioinformatics

Entrez	21812 Mouse 7046 Human
Uniprot	BAA05023 Mouse NM_004612 Human NP_001124388.1 Human NP_004603 Human NP_004603.1 Human P36897 Human
Product By Gene ID	7046
Alternate Names	AAT5 activin A receptor type II-like kinase, 53kD activin A receptor type II-like kinase, 53kDa Activin receptor-like kinase 5 ACVRLK4 ALK-5ALK5 EC 2.7.11 EC 2.7.11.30 LDS1A LDS2A Serine/threonine-protein kinase receptor R4 SKR4 tbetaR-I TbetaR-I TGFB1R1 TGF-beta receptor type I TGF-beta receptor type-1 TGF-beta type I receptor TGFR-1 transforming growth factor beta receptor I transforming growth factor, beta receptor 1 transforming growth factor, beta receptor I (activin A receptor type II-likekinase, 53kD) Transforming growth factor-beta receptor type I

Research Areas for TGF-beta RI/ALK-5

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Phospho-Specific
Protein Kinase