Home » Apolipoprotein E/ApoE » Apolipoprotein E/ApoE Antibodies » Apolipoprotein E/ApoE Antibody (EP1374Y)

We're moving to rndsystems.com. Come with us!

After August 17, 2026, Novus Biologicals products and services will no longer be available on this website; you will access all products and services on rndsystems.com. Create your R&D Systems online account today.

Register on R&D Systems

Apolipoprotein E/ApoE Antibody (EP1374Y)

 (5 Publications)
 (1 Review)
 See All Related
Submit a Review

Images

 

Product Details

Summary
Product Discontinued
View other related Apolipoprotein E/ApoE Primary Antibodies

Order Details


    • Catalog Number
      NB110-55466
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

Apolipoprotein E/ApoE Antibody (EP1374Y) Summary

Immunogen
A synthetic peptide corresponding to residues near the C-term of human apolipoprotein E was used as an immunogen.
Localization
Secreted
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
APOE
Purity
Tissue culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:250-500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:100-250
  • Immunoprecipitation 1:100
  • Western Blot 1:1000-10000
Theoretical MW
36 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control
Apolipoprotein E/ApoE Overexpression Lysate
Reviewed Applications
Read 1 Review rated 3
using
NB110-55466 in the following applications:
Publications
Read Publications using
NB110-55466 in the following applications:

  • WB
    4 publications

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
49% PBS, 0.05% BSA and 50% Glycerol
Preservative
0.01% Sodium Azide
Purity
Tissue culture supernatant

Notes

Produced using Abcam's RabMab® technology. RabMab® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Alternate Names for Apolipoprotein E/ApoE Antibody (EP1374Y)

  • APOE
  • Apo-E
  • Apolipoprotein E
  • apolipoprotein E3
  • late onset)
  • MGC1571

Background

The apolipoproteins are family of amphipathic lipoproteins that plays a crucial role in lipid metabolism. In particular, apolipoprotein E (apo E) is a major component of high density lipoproteins (HDL) chylomicrons and very low-density lipoprotein (VLDL), which functions to remove excess cholesterol. Apo E mediates lipid metabolism and cholesterol homeostasis by binding to several hepatic lipoprotein receptors, such as low density lipoprotein receptor (LDLR) and the LDLR-related protein (1). Apo E deficiency is linked to hyperlipoproteinemia type III; a genetic disorder characterized by elevated plasma cholesterol and triglyceride levels and accelerated coronary artery disease (2). Three major isoforms of Apo E (E2, E3, E4) has been identified, with E3 being the most common in human. E4 presence has been associated to increase probability of developing late-onset form of Alzheimer disease (3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

beta Amyloid
Antibody (MOAB-2) - B ...
NBP2-13075
Immunohistochemistry-Frozen beta Amyloid Antibody (MOAB-2) - BSA Free
Immunohistochemistry beta Amyloid Antibody (MOAB-2) - BSA Free
Immunocytochemistry/ Immunofluorescence beta Amyloid Antibody (MOAB-2) - BSA Free
(2 Reviews)
(75 Publications)
Species: Ba, Hu, Pm, Mu, Rt
Applications: DB, ELISA, IB, ICC/IF, IHC-FrFl, IHC, IHC-Fr,  IHC-P, IP, WB
UBE4A Antibody
(1G8) - Azide and BSA ...
H00009354-M08
ELISA UBE4A Antibody (1G8) - Azide and BSA Free
Immunocytochemistry/ Immunofluorescence UBE4A Antibody (1G8) - Azide and BSA Free
Western Blot UBE4A Antibody (1G8) - Azide and BSA Free
Species: Hu, Mu, Rt
Applications: ELISA, ICC/IF, WB
UBE4B Antibody -
BSA Free
NBP1-84943
Western Blot UBE4B Antibody - BSA Free
Immunohistochemistry-Paraffin UBE4B Antibody - BSA Free
Western Blot UBE4B Antibody - BSA Free
(1 Publication)
Species: Hu, Mu, Rt
Applications: IHC,  IHC-P, WB
LDLR Antibody
[Unconjugated]
AF2255
Immunohistochemistry LDLR Antibody [Unconjugated]
Western Blot LDLR Antibody [Unconjugated]
Western Blot LDLR Antibody [Unconjugated]
(51 Publications)
Species: Mu
Applications: Block, CyTOF-ready, Flow, IHC, WB
Presenilin-1
Antibody (APS 18)
NB100-74510
Western Blot Presenilin-1 Antibody (APS 18)
Immunocytochemistry/ Immunofluorescence Presenilin-1 Antibody (APS 18)
Immunocytochemistry/ Immunofluorescence Presenilin-1 Antibody (APS 18)
(1 Review)
(5 Publications)
Species: Hu, Mu, Pm, Rt
Applications: ELISA, ICC/IF, IHC,  IHC-P, IP, WB
Dihydrolipoamide
Dehydrogenase/DLD Ant ...
NBP1-31302
Western Blot Dihydrolipoamide Dehydrogenase/DLD Antibody - BSA Free
Western Blot Dihydrolipoamide Dehydrogenase/DLD Antibody - BSA Free
Immunocytochemistry/ Immunofluorescence Dihydrolipoamide Dehydrogenase/DLD Antibody - BSA Free
(1 Review)
(1 Publication)
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC,  IHC-P, KO, WB
ILT6/CD85e/LILRA3
Antibody (2E9) - Azid ...
H00011026-M01
Western Blot ILT6/CD85e/LILRA3 Antibody (2E9) - Azide and BSA Free
(6 Publications)
Species: Hu
Applications: ELISA, WB
ALDH9A1 Antibody -
BSA Free
NBP1-89150
Western Blot ALDH9A1 Antibody - BSA Free
Immunohistochemistry-Paraffin ALDH9A1 Antibody - BSA Free
Immunohistochemistry-Paraffin ALDH9A1 Antibody - BSA Free
(3 Publications)
Species: Hu
Applications: IHC,  IHC-P, WB
Apolipoprotein
A-I/ApoA1 Antibody - ...
NBP2-52979
Flow Cytometry Apolipoprotein A-I/ApoA1 Antibody - BSA Free
Western Blot Apolipoprotein A-I/ApoA1 Antibody - BSA Free
Immunocytochemistry/ Immunofluorescence Apolipoprotein A-I/ApoA1 Antibody - BSA Free
(1 Review)
Species: Hu, Mu
Applications: Flow, ICC/IF, IHC,  IHC-P, WB
Tau [p Ser396]
Antibody (SN62-09)
NBP2-67702
Immunocytochemistry/ Immunofluorescence Tau [p Ser396] Antibody (SN62-09)
Immunohistochemistry-Paraffin Tau [p Ser396] Antibody (SN62-09)
Immunohistochemistry-Paraffin Tau [p Ser396] Antibody (SN62-09)
(3 Publications)
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-Fr,  IHC-P, WB
DBT Antibody - BSA
Free
NBP1-89522
Immunohistochemistry-Paraffin DBT Antibody - BSA Free
Immunohistochemistry-Paraffin DBT Antibody - BSA Free
Immunohistochemistry-Paraffin DBT Antibody - BSA Free
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC,  IHC-P, WB
Lipoprotein
Lipase/LPL Antibody [ ...
AF7197
Immunohistochemistry Lipoprotein Lipase/LPL Antibody [Unconjugated]
Western Blot Lipoprotein Lipase/LPL Antibody [Unconjugated]
Immunocytochemistry Lipoprotein Lipase/LPL Antibody [Unconjugated]
(12 Publications)
Species: Hu, Mu
Applications: ICC, IHC, WB
GM-CSF
[Unconjugated]
7954-GM/CF
Bioactivity GM-CSF [Unconjugated]
(3 Publications)
Species: Hu
Applications: BA
LAMC2 Antibody
(CL2980) - BSA Free
NBP2-42388
Western Blot LAMC2 Antibody (CL2980) - BSA Free
Immunohistochemistry-Paraffin LAMC2 Antibody (CL2980) - BSA Free
Immunohistochemistry-Paraffin LAMC2 Antibody (CL2980) - BSA Free
(4 Publications)
Species: Hu
Applications: ICC/IF, IHC,  IHC-P, KD, WB
ACE/CD143 Antibody
[Unconjugated]
AF1513
Immunohistochemistry ACE/CD143 Antibody [Unconjugated]
Western Blot ACE/CD143 Antibody [Unconjugated]
Simple Western ACE/CD143 Antibody [Unconjugated]
(1 Review)
(9 Publications)
Species: Mu
Applications: CyTOF-ready, Flow, IHC, IP, Simple Western, WB
TNF-alpha
[Unconjugated]
210-TA
SDS-PAGE TNF-alpha [Unconjugated]
Bioactivity TNF-alpha [Unconjugated]
SEC-MALS TNF-alpha [Unconjugated]
(3 Reviews)
(850 Publications)
Species: Hu
Applications: BA
Thyroglobulin
Antibody (2H11 + 6E1)
NBP2-34294
Immunohistochemistry-Paraffin Thyroglobulin Antibody (2H11 + 6E1)
Immunohistochemistry Thyroglobulin Antibody (2H11 + 6E1)
Immunohistochemistry-Paraffin Thyroglobulin Antibody (2H11 + 6E1)
(3 Reviews)
(1 Publication)
Species: Hu, Mu, Rt
Applications: Flow, IHC,  IHC-P
Presenilin-2
Antibody (APS 26)
NB100-74513
Immunocytochemistry/ Immunofluorescence Presenilin-2 Antibody (APS 26)
Immunocytochemistry/ Immunofluorescence Presenilin-2 Antibody (APS 26)
Immunocytochemistry/ Immunofluorescence Presenilin-2 Antibody (APS 26)
Species: Hu, Mu, Pm, Rt
Applications: ELISA, ICC/IF, IHC,  IHC-P, IP, WB

Publications for Apolipoprotein E/ApoE Antibody (NB110-55466)(5)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.


Filter By Application
WB
(4)
All Applications
Filter By Species
Human
(4)
All Species

Review for Apolipoprotein E/ApoE Antibody (NB110-55466) (1) 31

Average Rating: 3
(Based on 1 review)
We have 1 review tested in 1 species: Mouse.

Reviews using NB110-55466:
Filter by Applications
IF
(1)
All Applications
Filter by Species
Mouse
(1)
All Species
Images Ratings Applications Species Date Details
  3
reviewed by:
Verified Customer
 IF Mouse 04/15/2009
View

Summary

ApplicationImmunofluorescence
Sample Testedmouse lung tissue
SpeciesMouse
LotEP1374Y

Product General Protocols

View specific protocols for Apolipoprotein E/ApoE Antibody (NB110-55466): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Apolipoprotein E/ApoE Antibody (NB110-55466). (Showing 1 - 2 of 2 FAQs).

  1. Which part of the APOE protein is recognize by APOE antibody (NB110-55466)? Is this antibody recognize residue 112 and 158?
    • The amino acid range this product was made to is between aa 267-317 of human Apolipoprotein E (Swiss Prot: P02649).
  2. There are three isoforms for human ApoE (E2, E3 and E4), I'm wondering which isoform does this antibody bind to?
    • The antibody was generated using a peptide sequence specific to the C-terminus of P02649-1 (UniProt). In regards to the different isoforms - they differ by a few amino acids - ApoE2 (cys112, cys158), ApoE3 (cys112, arg158), and ApoE4 (arg112, arg158). None of these amino acids are part of the immunogen sequence. They do, however, alter the structure and function of ApoE protein. I expect that the antibody should recognize all the different isoforms, although we don't have any experimental data on this.

Control Lysate(s)

Apolipoprotein E/ApoE Overexpression Lysate

Secondary Antibodies

 

Isotype Controls

Additional Apolipoprotein E/ApoE Products

Research Areas for Apolipoprotein E/ApoE Antibody (NB110-55466)

Find related products by research area.

Blogs on Apolipoprotein E/ApoE

There are no specific blogs for Apolipoprotein E/ApoE, but you can read our latest blog posts.

Contact Information

Product PDFs

  IHC Protocol
  SDS
  PDF Datasheet
  Request CofA

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Recent Reviews

3
5
0
4
0
3
1
2
0
1
0
 
 Verified Customer
04/15/2009
Application: IF
Species: Mouse
read this review

Bioinformatics

Gene Symbol APOE
Entrez
Uniprot