SREBP2 Products

SREBP2 Antibodies

Western Blot: SREBP2 Antibody (1D2) [NBP1-54446] - Lane1: HEp-2 cells. Lane 2: MCF-7 cells. Lane 3: LNCaP cells. Lane 4: HT1080 cells. Lane5 ZR75-1 cells.Immunocytochemistry/Immunofluorescence: SREBP2 Antibody (1D2) [NBP1-54446] - SREBP2 (1D2) antibody was tested in HeLa cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).
Species: Human, Chicken
Applications: WB, ELISA, GS, ICC/IF, IP
Host: Mouse Monoclonal
Western Blot: SREBP2 Antibody [NB100-74543] - Analysis of mouse liver (lane 1), rat liver (lane 2) and HepG2 (lane 3) cell lysates.Immunocytochemistry/Immunofluorescence: SREBP2 Antibody [NB100-74543] - Analysis of SREBP2 (green) showing staining in the cytoplasm of PC12 cells. (red) was stained with a flourescent red phalloidin and nuclei (blue) were stained with Hoechst or DAPI.
Species: Human, Mouse, Rat
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line and Raji human Burkitt's lymphoma cell line. Gels were loaded with 15 µg of nuclear extracts (Nuc). PVDF membrane was probed with 2 µg/mL of Goat Anti-Human SREBP2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7119) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <A class=NoLineLink href=SREBP2 was detected in immersion fixed HeLa human cervical epithelial carcinoma cell line using Goat Anti-Human SREBP2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7119) at 15 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # <A class=NoLineLink href=
Species: Human
Applications: WB, ChIP, ICC
Host: Goat Polyclonal


Applications: Func, ICC/IF
Applications: Func

SREBP2 Lysate

SREBP2 Protein

Species: Human
Applications: WB, ELISA, PA


Species: Human


SREBP2 encodes a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain.


Entrez Human
Uniprot Human
Product By Gene ID 6721
Alternate Names
  • SREBP2
  • BHLHD2
  • Class D basic helix-loop-helix protein 2
  • bHLHd2sterol regulatory element-binding protein 2
  • Sterol regulatory element-binding transcription factor 2
  • sterol regulatory element binding transcription factor 2

Bioinformatics Tool for SREBP2

Discover related pathways, diseases and genes to SREBP2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.

Related SREBP2 Blog Posts

Check out the latest blog posts on SREBP2.
SREBP2 - regulating cholesterol homeostasis and lipid metabolism
Sterol regulatory element-binding proteins (SREBP) are important transcription factors regulating the synthesis and uptake of lipids including cholesterol. This essential role in lipid metabolism makes investigations into the functions SREBPs im...    Read more.
SREBP: Gatekeeper of Cholesterol Homeostasis
SREBP1 (sterol-regulatory-element-binding protein 2) is a basic-helix-loop-helix-leucine zipper (bHLH-ZIP) transcription factor. It regulates sterol and cholesterol homeostasis by controlling enzymes involved in cholesterol synthesis and uptake, e.g....    Read more.
SREBPs: Global Regulator of Lipid Metabolism
Sterol regulatory element binding proteins (SREBPs) are indirectly required for cholesterol biosynthesis and for uptake and fatty acid biosynthesis. There are three known SREBP isoforms, SREBP1a, 1c and SREBP2; these have different roles in lipid synt...    Read more.
SREBP2: From Cholesterol Homeostasis to Cancer Invasion
Sterol-regulatory-element-binding protein 2 (SREBP2) is a transcription factor that regulates cholesterol homeostasis by controlling enzymes involved in cholesterol synthesis and uptake, e.g. HMG-CoA. Along with another transcription factor LXR, SREBP...    Read more.
ABCA1 Expression is Down-Regulated by SREBP microRNA
The ABCA1 (ATP-binding cassette transporter-A1) gene encodes a transmembrane protein, which plays a major role in phospholipid homeostasis by regulating cholesterol efflux from the cell. ABCA1 antibody studies have shown ABCA1 expression is up/down re...    Read more.
Read more SREBP2 related blogs.