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SREBP2 Products

SREBP2 Primary Antibodies

We have 7 SREBP2 Antibodies including 6 polyclonal and 1 monoclonal antibodies.

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SREBP2 Lysates

We have 1 SREBP2 Lysate.

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SREBP2 Peptides and Proteins

We have 1 SREBP2 Protein.

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SREBP2 RNAi

We have 1 SREBP2 RNAi.

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SREBP2 Kits

We have 2 SREBP2 Kits.

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Description

SREBP2 encodes a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain.

Bioinformatics

  • Entrez
  • Uniprot
  • Product By Gene ID6721
  • Alternate Names
    • SREBP2
    • sterol regulatory element binding transcription factor 2
    • Sterol regulatory element-binding transcription factor 2
    • SREBP2SREBP-2
    • bHLHd2sterol regulatory element-binding protein 2
    • Class D basic helix-loop-helix protein 2
    • BHLHD2

Diseases related to SREBP2

Discover more about diseases related to SREBP2.

  • Hypercholesterolemia
  • Obesity
  • Fatty Liver
  • Atherosclerosis
  • Diabetes Mellitus
  • Liver Carcinoma
  • Malignant Neoplasms
  • Insulin Resistance
  • Hyperlipidemia
  • Inflammation
  • Steatosis
  • Liver Diseases
  • Dyslipidemias
  • Neoplasms
  • Cardiovascular Diseases
  • Steatohepatitis
  • Liver Neoplasms
  • Diabetes Mellitus, Non-insulin-dependent
  • Malignant Neoplasm Of Prostate
  • Prostatic Neoplasms

Pathways for SREBP2

View related products by pathway and learn more about each of the pathways below.

  • Cholesterol Homeostasis
  • Secretion
  • Transport
  • Lipid Homeostasis
  • Cholesterol Efflux
  • Proteolysis
  • Pathogenesis
  • Localization
  • Cell Growth
  • Excretion
  • Cholesterol Transport
  • Fatty Acid Oxidation
  • Intestinal Cholesterol Absorption
  • Cell Proliferation
  • Cell Death
  • Nuclear Import
  • Gluconeogenesis
  • Myelination
  • Reverse Transcription
  • Insulin Secretion

PTMs for SREBP2

Learn more about PTMs related to SREBP2.

  • Cleavage
  • Phosphorylation
  • Oxidation
  • Reduction
  • Ubiquitination
  • Glycosylation
  • Acetylation
  • Prenylation
  • Sumoylation
  • Dephosphorylation
  • Carboxylation
  • Biotinylation
  • Nitration
  • Methylation
  • Cysteinylation
  • Farnesylation
  • Deacetylation

Bioinformatics Tool for SREBP2

Discover related pathways, diseases and genes to SREBP2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.


 

Related SREBP2 Blog Posts

Check out the latest blog posts on SREBP2.
SREBPs: Global Regulator of Lipid Metabolism
Sterol regulatory element binding proteins (SREBPs) are indirectly required for cholesterol biosynthesis and for uptake and fatty acid biosynthesis. There are three known SREBP isoforms, SREBP1a, 1c and SREBP2; these have different roles i...    Read more.
SREBP2: From Cholesterol Homeostasis to Cancer Invasion
Sterol-regulatory-element-binding protein 2 (SREBP2) is a transcription factor that regulates cholesterol homeostasis by controlling enzymes involved in cholesterol synthesis and uptake, e.g. HMG-CoA. Along with another transcription facto...    Read more.
ABCA1 Expression is Down-Regulated by SREBP microRNA
The ABCA1 (ATP-binding cassette transporter-A1) gene encodes a transmembrane protein, which plays a major role in phospholipid homeostasis by regulating cholesterol efflux from the cell. ABCA1 antibody studies have shown ABCA1 expression i...    Read more.

Read more SREBP2 related blogs.