Histone proteins are nuclear proteins which interact with DNA, condense and provide structure to chromosomes.  Histones are prone to several post-translational modifications (PTMs).  By modifying amino acid residues on the tail of the core histones it is possible to alter the availability of the DNA to interact with other nuclear proteins. PTMs of Histone tails include: methylation, acetylation, phosphorylation, ubiquitination, sumoylation, citrullination and ADP-ribosylation.  Histone PTMs play a role in gene regulation, DNA repair and chromosome condensation during cell division.  To learn more, view our Modified Histone Map poster or request a copy here. Novus provides a line of multi-assay validated modified histone antibodies called Epi-Plus™ antibodies. Learn more about Epi-Plus™ here.

Browse our modified histone antibodies including:

• H3K4Me2 Antibody
• H3K4Me3 Antibody
• H3K9Me3 Antibody
• H3K36Me1 Antibody
• H3K36Me2 Antibody
• H4K20Me1 Antibody

All Modified Histone Antibodies, Lysates, Proteins and RNAi

Research Cloud — Top terms most co-occuring with "Histone Modification" in scientific publications. Click to explore.