Angiogenesis

Angiogenesis is the process of forming new blood vessels from preexisting blood vessels. This process occurs during embryonic development and is generally limited in adults to wound healing and menstruation. Angiogenesis is required for cancer metastasis, thus it has become a widely studied research area. Tumor angiogenesis refers to the proliferation of a network of blood vessels that penetrates into cancerous growths. This blood vessel network provides nutrients and oxygen to the tumor and removes waste products, thus allowing the tumor to grow. Angiogenesis is regulated by pro- angiogenic factors and anti-angiogenic factors.  The balance between pro-angiogenic factors and anti-angiogenic factors is often referred to as the angiogenic switch.  When new blood vessels are needed, pro-angiogenic factors increase, including vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), epidermal growth factor (EGF), and transforming growth factor-beta (TGF-b), which effectively initiate the division of endothelial vascular cells.

All Angiogenesis Antibodies, Lysates, Proteins and RNAi

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